SCHEMBL2685876

SCHEMBL2685876

CCCCCCCCC(=O)C1(COCCCC)c2ccccc2-c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.42
SOAT1 P35610 2/20 0.41
MTTP P55157 1/20 0.39
CNR2 P34972 1/20 0.39
PTPN11 Q06124 1/20 0.39
PLA2G4B P0C869 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TDP2 O95551 1/20 0.38
MAPT P10636 1/20 0.38
TSHR P16473 1/20 0.38
LMNA P02545 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2688055 1.00 PDK2 (0.42) PDK2SOAT1MTTPCNR2PTPN11
SCHEMBL2686846 1.00 PDK2 (0.42) PDK2SOAT1MTTPCNR2PTPN11
SCHEMBL14977678 0.99 PDK2 (0.44) PDK2SOAT1CNR2PTPN11PLA2G4B
SCHEMBL2686331 0.99 PDK2 (0.41) PDK2SOAT1MTTPALDH1A1TDP2
SCHEMBL14977552 0.97 PDK2 (0.40) PDK2SOAT1MTTPCNR2PTPN11
SCHEMBL2687540 0.97 PDK2 (0.42) PDK2SOAT1CNR2PTPN11PLA2G4B
SCHEMBL2685996 0.97 PDK2 (0.42) PDK2SOAT1CNR2PTPN11PLA2G4B
SCHEMBL2687530 0.97 PDK2 (0.42) PDK2SOAT1CNR2PTPN11PLA2G4B
SCHEMBL2689532 0.96 PDK2 (0.41) PDK2SOAT1MTTPCNR2ALDH1A1
SCHEMBL2689008 0.95 SOAT1 (0.41) PDK2SOAT1CNR2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
CN-107207657-B Process for preparing spherical polymerization catalyst components for olefin polymerization 格雷斯公司 2020-03-03 CN disclosed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP disclosed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO disclosed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US disclosed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US disclosed