SCHEMBL26860

SCHEMBL26860

NC1=NC(=O)CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8392041 0.74
Hydrochloric Acid SCHEMBL7968129 0.72
Hydantoin SCHEMBL9391323 0.69
SCHEMBL4525780 0.67
Thiohydantoin SCHEMBL17153849 0.67
SCHEMBL17153757 0.65
SCHEMBL2618034 0.65
Hydrochloric Acid SCHEMBL11692084 0.63
SCHEMBL10821674 0.62
SCHEMBL84315 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111925846-B High-efficiency thioether and thiophene removing solvent and application thereof 中国石油集团工程股份有限公司 2024-10-01 CN claimed
US-20130157252-A1 DIAGNOSTIC MARKER FOR KIDNEY DISEASES AND USE THEREOF HUMAN METABOLOME TECHNOLOGIES, INC. (JP) 2013-06-20 US claimed
EP-2565646-A1 DIAGNOSTIC MARKER FOR KIDNEY DISEASES AND USE THEREOF Sysmex Corporation (JP) 2013-03-06 EP claimed
CN-102859357-A Marker for diagnosing kidney disease and use thereof SYSMEX CORP 2013-01-02 CN claimed
US-20090104116-A1 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF JERINI AG (DE) 2009-04-23 US claimed
US-20050178049-A1 Diesel fuel composition TEXACO, INC. 2005-08-18 US claimed
US-6610700-B2 Inhibit binding of integrins to their ligands, use in immune or inflammatory disorders; 3-(4-((2,6-Naphthyridinyl)amino)-phenyl)-2-((2-(1-ethylpropyl)-3-oxo-1 -cyclopentenyl) amino)-propionic acid, for example CELLTECH R & D LIMITED (GB) 2003-08-26 US claimed
EP-0431930-B1 Developer for electrophotography SHARP KK (JP) 1996-10-23 EP claimed
EP-0381628-B1 Glycocyamidine derivatives NIPPON ZOKI PHARMACEUTICAL CO (JP) 1994-12-21 EP claimed
US-5266433-A Imidazole additive SHARP KABUSHIKI KAISHA (JP) 1993-11-30 US claimed
EP-0431930-A2 Developer for electrophotography SHARP KABUSHIKI KAISHA (JP) 1991-06-12 EP claimed
US-4957936-A TEST REAGENT FOR RENAL FAILURE DIAGNOSIS NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) 1990-09-18 US claimed
EP-0381628-A2 Glycocyamidine derivatives NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) 1990-08-08 EP claimed
JP-2131567-A None JP disclosed
JP-2057261-A None JP disclosed
JP-1186708-A None JP disclosed
JP-H0257261-A DEODORANT LION CORP 1990-02-27 JP disclosed
JP-H01186708-A FIRE-RESISTANT INSULATING COMPOSITION HITACHI CABLE LTD 1989-07-26 JP disclosed
US-4110445-A METHOD FOR ANTAGONIZING ALDOSTERONIC ACTION AND INDUCING DIURESIS BY ADMINISTERING A TETRASUBSTITUTED IMIDAZOLIDINE AMERICAN CYANAMID COMPANY (US) 1978-08-29 US disclosed
US-4044021-A Tetrasubstituted imidazolidine diuretics useful in the treatment of hyperaldosteronism AMERICAN CYANAMID COMPANY (US) 1977-08-23 US disclosed