⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25358969 | 0.78 | — | — | |
| SCHEMBL25467342 | 0.77 | — | — | |
| SCHEMBL18813480 | 0.72 | — | — | |
| SCHEMBL19014429 | 0.70 | — | — | |
| SCHEMBL5394486 | 0.69 | — | — | |
| SCHEMBL21961608 | 0.69 | — | — | |
| SCHEMBL21961800 | 0.69 | — | — | |
| SCHEMBL20886818 | 0.65 | — | — | |
| SCHEMBL14603828 | 0.65 | — | — | |
| SCHEMBL24929114 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11826351-B2 | Compounds useful as kinase inhibitors | LOXO ONCOLOGY INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-20230372298-A1 | COMPOUNDS USEFUL AS KINASE INHIBITORS | LOXO ONCOLOGY, INC. | 2023-11-23 | — | — | US | disclosed |