SCHEMBL2686187

SCHEMBL2686187

C=CC(=O)OCCC.C=CC(=O)OCCCC

nearest known ligand 0.92

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.92
HPGD P15428 1/20 0.92
ALDH1A1 P00352 4/20 0.65
CYP3A4 P08684 1/20 0.65
ATM Q13315 1/20 0.63
HCAR2 Q8TDS4 4/20 0.55
TP53 P04637 2/20 0.54
HIF1A Q16665 2/20 0.54
HSD17B10 Q99714 1/20 0.54
THRB P10828 2/20 0.49
MAPT P10636 1/20 0.47
RAB9A P51151 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11582291 0.96 TSHR (1.00) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1330627 0.96
SCHEMBL5681395 0.96 TSHR (1.00) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL15037 0.96
SCHEMBL1331857 0.96
SCHEMBL28823508 0.94 TSHR (0.81) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1493269 0.94 TSHR (0.96) TSHRHPGDALDH1A1CYP3A4ATM
Methyl Alcohol SCHEMBL3865866 0.94 TSHR (0.96) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL1160870 0.94 TSHR (0.96) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL6763649 0.94 TSHR (0.96) TSHRHPGDALDH1A1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7250472-B1 Can be processed into thermoformable acrylic sheet material with variegated non-homogeneous granite appearance and, bathware, comprising a matrix of polymethyl methacrylate having dispersed within it particles of a thermoplastic LUCITE INTERNATIONAL, INC. (US) 2007-07-31 US claimed
EP-1153081-B1 ACRYLIC COMPOSITIONS LUCITE INT INC (US) 2006-03-29 EP claimed
EP-1153081-A4 ACRYLIC COMPOSITIONS INEOS ACRYLICS INC (US) 2002-11-20 EP claimed
EP-1153081-A1 ACRYLIC COMPOSITIONS ICI Acrylics, Inc. (US) 2001-11-14 EP claimed
WO-2000024825-A1 ACRYLIC COMPOSITIONS ICI ACRYLICS, INC. (US) 2000-05-04 WO claimed
EP-0856032-A4 ACRYLIC COMPOSITIONS ICI ACRYLICS INC (US) 1999-09-22 EP claimed
US-5880207-A MATRIX OF POLYMETHYL METHARYLATE HAVING PARTICLES DISPERSED THEREIN COMPOSED OF A METHYL METHACRYLATE COPOLYMER; SMOOTH, GRANITE APPEARANCE FOR SPAS AND BATHWARE ICI ACRYLICS INC. (US) 1999-03-09 US claimed
EP-0856032-A1 ACRYLIC COMPOSITIONS ICI Acrylics, Inc. (US) 1998-08-05 EP claimed
WO-1997014749-A1 ACRYLIC COMPOSITIONS ICI ACRYLICS INC. (US) 1997-04-24 WO claimed
EP-3520772-B1 COSMETIC RAW MATERIAL USING CORE-CORONA TYPE MICROPARTICLES AND OIL-IN-WATER TYPE EMULSION COSMETIC SHISEIDO CO LTD (JP) 2023-12-20 EP disclosed
EP-3526297-A1 THERMOFORMABLE AND SCRATCH-RESISTANT PHOTOPOLYMER COATINGS Université de Haute Alsace (FR) 2019-08-21 EP disclosed
US-20170110759-A1 SOLID ELECTROLYTE BASF SE (DE) 2017-04-20 US disclosed
EP-3120408-A1 SOLID ELECTROLYTE BASF SE (DE) 2017-01-25 EP disclosed
EP-2265672-B1 FLAME-RETARDANT SCRATCH-RESISTANT THERMOPLASTIC RESIN COMPOSITION WITH IMPROVED COMPATIBILITY CHEIL IND INC (KR) 2016-09-28 EP disclosed
US-6359081-B1 FOR COMPATIBILIZING TAKIRON CO., LTD. (JP) 2002-03-19 US disclosed
EP-0838484-A1 FUNCTIONAL BLOCK COPOLYMER AND PROCESS FOR PREPARING THE SAME TAKIRON CO. LTD. (JP) 1998-04-29 EP disclosed
US-5455154-A Storage stable, scratch resistance; vinyl alcohol copolymer binders for high speed hardeners AGFA GEVAERT, AG (DE) 1995-10-03 US disclosed
EP-0560508-A1 Aqueous coating compositions ZENECA RESINS BV (NL) 1993-09-15 EP disclosed
EP-0418661-A1 Use of copolymerisates based on long chain unsaturated esters and ethylenically unsaturated carbonic acids for hydrophobing of leather and fur pelts BASF Aktiengesellschaft (DE) 1991-03-27 EP disclosed
EP-0058403-B1 FLAME RETARDANT POLYARYLATE COMPOSITIONS AMOCO CORPORATION (US) 1986-01-08 EP disclosed