Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 9/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.31 |
| ▸ | CDK2 | P24941 | 6/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CDK4 | P11802 | 2/20 | 0.31 |
| ▸ | CCND1 | P24385 | 2/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.31 |
| ▸ | CDK7 | P50613 | 2/20 | 0.31 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26868252 | 1.00 | MAP3K12 (0.33) | MAP3K12KDM4EMEN1NPC1MAPT | |
| SCHEMBL26868250 | 1.00 | MAP3K12 (0.33) | MAP3K12KDM4EMEN1NPC1MAPT | |
| SCHEMBL26868861 | 0.95 | MAP3K12 (0.33) | MAP3K12KDM4EMEN1NPC1MAPT | |
| SCHEMBL26868590 | 0.95 | MAP3K12 (0.35) | MAP3K12KDM4EMEN1NPC1MAPT | |
| SCHEMBL26868320 | 0.84 | CHEK1 (0.34) | MAP3K12KDM4EMEN1NPC1MAPT | |
| SCHEMBL26868315 | 0.84 | CHEK1 (0.34) | MAP3K12KDM4EMEN1NPC1MAPT | |
| SCHEMBL26868318 | 0.84 | CHEK1 (0.34) | MAP3K12KDM4EMEN1NPC1MAPT | |
| SCHEMBL26874424 | 0.83 | KDM4E (0.36) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL26868158 | 0.82 | KDM4E (0.35) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL26868112 | 0.82 | KDM4E (0.35) | KDM4EMEN1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |