SCHEMBL2686863

SCHEMBL2686863

CCCCCC(=O)C1(COCCC)c2ccccc2-c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 2/20 0.39
PDK2 Q15119 3/20 0.38
MTTP P55157 1/20 0.38
CNR2 P34972 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2689008 0.99 SOAT1 (0.41) SOAT1PDK2CNR2TSHRCES2
SCHEMBL2688054 0.99 SOAT1 (0.41) SOAT1PDK2CNR2TSHRCES2
SCHEMBL2687565 0.99 SOAT1 (0.41) SOAT1PDK2CNR2TSHRCES2
SCHEMBL14977552 0.96 PDK2 (0.40) SOAT1PDK2MTTPCNR2
SCHEMBL2685785 0.96 MTTP (0.38) PDK2MTTPCNR2CES2CES1
SCHEMBL2689532 0.95 PDK2 (0.41) SOAT1PDK2MTTPCNR2TP53
SCHEMBL2686331 0.95 PDK2 (0.41) SOAT1PDK2MTTPTSHR
SCHEMBL2685996 0.93 PDK2 (0.42) SOAT1PDK2CNR2TP53CYP3A4
SCHEMBL2686846 0.93 PDK2 (0.42) SOAT1PDK2MTTPCNR2TSHR
SCHEMBL2687530 0.93 PDK2 (0.42) SOAT1PDK2CNR2TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
CN-107207657-B Process for preparing spherical polymerization catalyst components for olefin polymerization 格雷斯公司 2020-03-03 CN disclosed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP disclosed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO disclosed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US disclosed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US disclosed