Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 8/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26870888 | 0.80 | KDM4E (0.36) | CDK2KDM4EALDH1A1CCNA2CCNA1 | |
| SCHEMBL26871380 | 0.79 | CSNK2A1 (0.52) | CDK2CSNK2A1BCL6 | |
| SCHEMBL26870923 | 0.78 | CCNT1 (0.31) | CDK2KDM4EALDH1A1CCNA2CCNA1 | |
| SCHEMBL26871061 | 0.76 | PIK3CB (0.33) | CDK2CCNA2CCNA1 | |
| SCHEMBL26870935 | 0.76 | CDK2 (0.39) | CDK2KDM4EALDH1A1CHEK1CCNA2 | |
| SCHEMBL15288383 | 0.75 | CDK2 (0.61) | CDK2KDM4EALDH1A1CSNK2A1GLA | |
| SCHEMBL26867735 | 0.75 | CCNT1 (0.56) | CDK2CCNA2CCNA1CSNK2A1MAPKAPK2 | |
| SCHEMBL18343698 | 0.73 | KDM4E (0.59) | CDK2KDM4EALDH1A1CSNK2A1GLA | |
| SCHEMBL28420899 | 0.71 | CDK2 (0.49) | CDK2KDM4EALDH1A1CSNK2A1GLA | |
| SCHEMBL26871261 | 0.69 | CDK2 (0.46) | CDK2KDM4EALDH1A1CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |