Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2688394 | 1.00 | — | — | |
| Bromide SCHEMBL2687875 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6325454 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL28381463 | 0.82 | CYP3A4 (0.33) | — | |
| Bromide SCHEMBL20876 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL1586512 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL29104164 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL84 | 0.82 | — | — | |
| Bromide SCHEMBL14964797 | 0.82 | — | — | |
| Bromide SCHEMBL1003966 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3961033-A | FROM CHLORINE AND ETHYLENE DIBROMIDE | ETHYL CORPORATION (US) | 1976-06-01 | — | — | US | claimed |
| EP-1896512-B1 | BROMINATED STYRENIC POLYMERS AND THEIR PREPARATION | ALBEMARLE CORP (US) | 2016-10-26 | — | — | EP | disclosed |
| EP-1963377-B1 | BROMINATED ANIONIC STYRENIC POLYMERS AND THEIR PREPARATION | ALBEMARLE CORP (US) | 2016-08-10 | — | — | EP | disclosed |
| US-8168723-B2 | Brominated styrenic polymers and their preparation | ALBEMARLE CORPORATION (US) | 2012-05-01 | — | — | US | disclosed |
| US-8071688-B2 | Brominated anionic styrenic polymers and their preparation | ALBEMARLE CORPORATION (US) | 2011-12-06 | — | — | US | disclosed |
| US-20100087620-A1 | Brominated Anionic Styrenic Polymers and Their Preparation | ALBEMARLE CORPORATION (US) | 2010-04-08 | — | — | US | disclosed |
| US-20100081762-A1 | Brominated Styrenic Polymers and Their Preparation | ALBEMARLE CORPORATION (US) | 2010-04-01 | — | — | US | disclosed |
| US-7632893-B2 | Brominated styrenic polymers and their preparation | ALBEMARLE CORPORATION (US) | 2009-12-15 | — | — | US | disclosed |
| EP-1963377-A1 | BROMINATED ANIONIC STYRENIC POLYMERS AND THEIR PREPARATION | Albermarle Corporation (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1896512-A1 | BROMINATED STYRENIC POLYMERS AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007076369-A1 | BROMINATED ANIONIC STYRENIC POLYMERS AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007005233-A1 | BROMINATED STYRENIC POLYMERS AND THEIR PREPARATION | ALBEMARLE CORPORATION (US) | 2007-01-11 | — | — | WO | disclosed |
| US-20070004870-A1 | Brominated styrenic polymers and their preparation | ALBEMARLE CORPORATION | 2007-01-04 | — | — | US | disclosed |
| EP-0179277-B1 | MEDICAL COMPOSITION FOR EXTERNAL APPLICATION | Kao Corporation (JP) | 1988-11-02 | — | — | EP | disclosed |
| US-4686211-A | Medical composition for external application | KAO CORPORATION (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0179277-A1 | Medical composition for external application | Kao Corporation (JP) | 1986-04-30 | — | — | EP | disclosed |
| US-3961033-A | FROM CHLORINE AND ETHYLENE DIBROMIDE | ETHYL CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |