SCHEMBL2687672

SCHEMBL2687672

N[C@@H](CC(=O)O)C(=O)OC(=O)[C@@H](N)Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.58
PKM P14618 1/20 0.58
PTGS1 P23219 1/20 0.58
XIAP P98170 1/20 0.58
SLC7A5 Q01650 1/20 0.58
SLC15A1 P46059 2/20 0.54
LTA4H P09960 3/20 0.51
CPA1 P15085 2/20 0.50
CPB1 P15086 1/20 0.50
CPA3 P15088 1/20 0.50
CPB2 Q96IY4 1/20 0.50
SLC1A3 P43003 2/20 0.46
SLC1A2 P43004 2/20 0.46
SLC1A1 P43005 2/20 0.46
HDAC8 Q9BY41 2/20 0.45
TYR P14679 1/20 0.45
SRR Q9GZT4 2/20 0.45
CTSC P53634 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28127104 1.00 ALPI (0.58) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL288607 0.91 SLC7A5 (0.68) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL28820471 0.91 SLC7A5 (0.68) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL8835936 0.91 SLC7A5 (0.68) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL29160724 0.90 SLC7A5 (0.66) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL3926429 0.89 ALPI (0.56) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL4778519 0.89 SLC7A5 (0.56) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL28203854 0.87 SLC7A5 (0.60) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL21495214 0.85 SLC7A5 (0.59) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL2494942 0.85 SLC7A5 (0.59) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0986575-B1 METHOD FOR PREPARING SALTS OF ASPARTAME FROM N-PROTECTED ASPARTAME HOLLAND SWEETENER CO (NL) 2003-04-23 EP claimed
EP-0929233-B1 POWDERED SWEETENER COMPOSITION FOR ANIMAL FEED PANCOSMA S A POUR L IND DES PR (CH) 2002-12-04 EP claimed
CN-1092933-C Powdered sweetener composition for animal feed PANCOSMA BIOCHEMICAL PRODUCTS (CH) 2002-10-23 CN claimed
EP-1032372-B1 MASKING AGENT IN POWDER FORM FOR PHARMACEUTICAL FLAVOURS PANCOSMA S A POUR L IND DES PR (CH) 2002-10-02 EP claimed
EP-1084138-B1 METHOD FOR PREPARING ASPARTYL CYCLOHEXYLALANINAMIDE AVENTIS PHARMA SA (FR) 2002-01-30 EP claimed
EP-1032372-A1 MASKING AGENT IN POWDER FORM FOR PHARMACEUTICAL FLAVOURS Pancosma S.A. pour l'Industrie des Produits Biochimiques (CH) 2000-09-06 EP claimed
CN-1224336-A Powdered sweetener composition for animal feed PANCOSMA S A LAB (CH) 1999-07-28 CN claimed
EP-0929233-A1 POWDERED SWEETENER COMPOSITION FOR ANIMAL FEED Pancosma S.A. pour l'Industrie des Produits Biochimiques (CH) 1999-07-21 EP claimed
EP-0928564-A1 Pulverulent sweetener for human nutrition Laboratoires Pancosma S.A. (CH) 1999-07-14 EP claimed
WO-1999030573-A1 POWDER SWEETENER FOR HUMAN FOOD PANCOSMA SOCIETE ANONYME POUR L'INDUSTRIE DES PRODUITS BIOCHIMIQUES (CH) 1999-06-24 WO claimed
WO-1999027915-A1 MASKING AGENT IN POWDER FORM FOR PHARMACEUTICAL FLAVOURS PANCOSMA SOCIETE ANONYME POUR L'INDUSTRIE DES PRODUITS BIOCHIMIQUES (CH) 1999-06-10 WO claimed
EP-0920861-A1 Taste masking powders for pharmaceuticals Laboratoires Pancosma S.A. (CH) 1999-06-09 EP claimed
WO-1998003082-A1 POWDERED SWEETENER COMPOSITION FOR ANIMAL FEED PANCOSMA SOCIETE ANONYME POUR L'INDUSTRIE DES PROD (CH) 1998-01-29 WO claimed
US-8491945-B2 Oral compositions containing oxidized Camellia COLGATE-PALMOLIVE COMPANY (US) 2013-07-23 US disclosed
CN-102858310-A Fluoride free and anionic surfactant free dentifrice having a high micro efficacy COLGATE PALMOLIVE CO 2013-01-02 CN disclosed
US-20120283174-A1 ANTIBIOFILM GLYCOPEPTIDES ORAL HEALTH AUSTRALIA PTY. LTD. (AU) 2012-11-08 US disclosed
US-4079151-A Frosted coating for sweetened foods GENERAL FOODS CORPORATION (US) 1978-03-14 US disclosed
US-4031258-A Inorganic salts of dipeptide sweeteners GENERAL FOODS CORPORATION (US) 1977-06-21 US disclosed
US-4029701-A Sweetening with hydrohalide salts of dipeptide sweeteners GENERAL FOODS CORPORATION (US) 1977-06-14 US disclosed
US-3934047-A Taste modifier for artificial sweeteners GENERAL FOODS CORPORATION (US) 1976-01-20 US disclosed