Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 12/20 | 0.61 |
| ▸ | RAB9A | P51151 | 12/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.56 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26885198 | 0.96 | NPC1 (0.66) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26885195 | 0.92 | TRPV1 (0.68) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26885196 | 0.92 | TRPV1 (0.68) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26885203 | 0.92 | DEGS1 (0.60) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26885210 | 0.91 | NPC1 (0.60) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26885211 | 0.88 | TRPV1 (0.66) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26885205 | 0.88 | TRPV1 (0.66) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26885199 | 0.88 | TRPV1 (0.69) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26885218 | 0.85 | DEGS1 (0.64) | TRPV1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26889461 | 0.84 | DEGS1 (0.57) | TRPV1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381159-A1 | SMALL MOLECULE INHIBITORS OF CORONAVIRUS ATTACHMENT AND ENTRY, METHODS AND USES THEREOF | UNIVERSITY OF MIAMI | 2023-11-30 | — | — | US | disclosed |
| US-20230381159-A1 | SMALL MOLECULE INHIBITORS OF CORONAVIRUS ATTACHMENT AND ENTRY, METHODS AND USES THEREOF | UNIVERSITY OF MIAMI | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381159-A1 | SMALL MOLECULE INHIBITORS OF CORONAVIRUS ATTACHMENT AND ENTRY, METHODS AND USES THEREOF | ACE2, ACE, SARS1 | TRPV1 1641/4885NPC1 72/4885RAB9A 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.