Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 13/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.46 |
| ▸ | CDK2 | P24941 | 5/20 | 0.45 |
| ▸ | JAK3 | P52333 | 4/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.45 |
| ▸ | PLK4 | O00444 | 3/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 3/20 | 0.45 |
| ▸ | MARK3 | P27448 | 3/20 | 0.45 |
| ▸ | TYK2 | P29597 | 3/20 | 0.45 |
| ▸ | CLK2 | P49760 | 3/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30633170 | 1.00 | JAK2 (0.51) | JAK2LRRK2HRH3MAP4K4CDK2 | |
| SCHEMBL26686269 | 0.87 | JAK2 (0.50) | JAK2LRRK2MAP4K4CDK2JAK3 | |
| SCHEMBL26686087 | 0.87 | JAK2 (0.52) | JAK2LRRK2MAP4K4CDK2JAK3 | |
| SCHEMBL31420129 | 0.87 | JAK2 (0.52) | JAK2LRRK2MAP4K4CDK2JAK3 | |
| SCHEMBL26686310 | 0.87 | JAK2 (0.55) | JAK2LRRK2MAP4K4CDK2JAK3 | |
| SCHEMBL26685747 | 0.86 | LRRK2 (0.58) | JAK2LRRK2MAP4K4CDK2JAK3 | |
| SCHEMBL31240448 | 0.86 | JAK2 (0.51) | JAK2LRRK2MAP4K4CDK2JAK3 | |
| SCHEMBL26686112 | 0.86 | JAK2 (0.51) | JAK2LRRK2MAP4K4CDK2JAK3 | |
| SCHEMBL31240693 | 0.85 | JAK2 (0.50) | JAK2LRRK2MAP4K4CDK2JAK3 | |
| SCHEMBL26685988 | 0.85 | JAK2 (0.50) | JAK2LRRK2MAP4K4CDK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |