Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 11/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420740 | 1.00 | PIK3C3 (0.45) | PIK3C3GSK3BJAK3MAPK1AAK1 | |
| SCHEMBL30633351 | 1.00 | PIK3C3 (0.45) | PIK3C3GSK3BJAK3MAPK1AAK1 | |
| SCHEMBL31420477 | 0.90 | JAK3 (0.41) | PIK3C3GSK3BJAK3MAPK1MAPK14 | |
| SCHEMBL31420591 | 0.90 | JAK3 (0.41) | PIK3C3GSK3BJAK3MAPK1MAPK14 | |
| SCHEMBL30633291 | 0.90 | PIK3C3 (0.51) | PIK3C3AAK1 | |
| SCHEMBL31420510 | 0.90 | PIK3C3 (0.51) | PIK3C3AAK1 | |
| SCHEMBL26888164 | 0.90 | PIK3C3 (0.51) | PIK3C3AAK1 | |
| SCHEMBL31420562 | 0.87 | PIK3C3 (0.41) | PIK3C3GSK3BMAPK14 | |
| SCHEMBL26686349 | 0.87 | PIK3C3 (0.41) | PIK3C3GSK3BMAPK14 | |
| SCHEMBL26686694 | 0.86 | PIK3C3 (0.42) | PIK3C3GSK3BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218201-A1 | IKK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |