Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 10/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 8/20 | 0.44 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26684598 | 0.88 | PBRM1 (0.41) | IKBKBPBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL26684798 | 0.82 | PBRM1 (0.37) | IKBKBPBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL31570168 | 0.78 | SMARCA2 (0.47) | QDPRPBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL26685057 | 0.78 | SMARCA2 (0.47) | QDPRPBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL26685046 | 0.78 | PBRM1 (0.41) | IKBKBPBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL31570150 | 0.78 | PBRM1 (0.41) | IKBKBPBRM1SMARCA2SMARCA4NR1I2 | |
| SCHEMBL26888980 | 0.77 | SMARCA2 (0.57) | PBRM1SMARCA2SMARCA4SIGMAR1NR1I2 | |
| Hydrochloric Acid SCHEMBL31548724 | 0.76 | PBRM1 (0.60) | QDPRIKBKBPBRM1SMARCA2SMARCA4 | |
| SCHEMBL23606907 | 0.76 | TLR9 (0.42) | QDPRIKBKBPBRM1SMARCA2SMARCA4 | |
| SCHEMBL31570184 | 0.76 | PBRM1 (0.41) | QDPRIKBKBPBRM1SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220129-A1 | BENZOYPARAZINE PYRAZINES ANE THEIR USES | FOGHORN THERAPEUTICS INC. (US) | 2023-11-16 | — | — | WO | disclosed |