⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934846 | 0.94 | — | — | |
| SCHEMBL9428449 | 0.92 | — | — | |
| SCHEMBL270498 | 0.86 | — | — | |
| SCHEMBL9082457 | 0.78 | — | — | |
| SCHEMBL1680615 | 0.78 | — | — | |
| SCHEMBL2005497 | 0.78 | — | — | |
| SCHEMBL20397432 | 0.78 | — | — | |
| SCHEMBL9082275 | 0.77 | CYP4F2 (0.32) | — | |
| SCHEMBL16243885 | 0.77 | CA12 (0.32) | — | |
| SCHEMBL628308 | 0.77 | KCNH2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063550-A | Novel brucella-resistant polypeptide and preparation method and application thereof | 包头市第四医院 | 2024-05-24 | — | — | CN | disclosed |
| EP-2782922-A1 | ANTIBACTERIAL TYLOSIN DERIVATIVES AND METHODS FOR THEIR PREPARATION | Bayer Intellectual Property GmbH (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-1910317-B1 | 1-AMINO LINKED COMPOUNDS | LILLY CO ELI (US) | 2013-07-03 | — | — | EP | disclosed |
| WO-2013076169-A1 | ANTIBACTERIAL TYLOSIN DERIVATIVES AND METHODS FOR THEIR PREPARATION | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-30 | — | — | WO | disclosed |
| EP-1910274-B1 | PHENYL COMPOUNDS | LILLY CO ELI (US) | 2012-08-08 | — | — | EP | disclosed |
| US-8133907-B2 | Type II diabetes, obesity, hyperglycemia and a lipid disorder selected from dyslipidemia, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, low HDL and high LDL; additionally comprising metformin | ELI LILLY AND COMPANY (US) | 2012-03-13 | — | — | US | disclosed |
| US-8106090-B2 | Antidiabetic agents; prevent of non-insulin dependent diabetes | ELI LILLY AND COMPANY (US) | 2012-01-31 | — | — | US | disclosed |
| US-8076514-B2 | Dipeptidyl peptidase IV inhibitors; Type II diabetes; 2-[(2S,3R)-3-Amino-2-hydroxy-4-(2,4,5-trifluoro-phenyl)-butyl]-N-tert-butyl-4-chloro-benzamide Hydrochloride | ELI LILLY AND COMPANY (US) | 2011-12-13 | — | — | US | disclosed |
| EP-1912946-B1 | PYRIDINE DERIVATIVES AS DIPEPTEDYL PEPTIDASE INHIBITORS | LILLY CO ELI (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20080221217-A1 | Phenyl Compounds and Their Use in the Treatment of Type II Diabetes | ELI LILLY AND COMPANY | 2008-09-11 | — | — | US | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |
| CN-1495153-A | 2-methoxy diphenyl ketone compound intermediate and its preparation method | 谷 | 2004-05-12 | — | — | CN | disclosed |
| CN-1147456-C | Fungicidal 2-methoxybenzophenones | 谷 | 2004-04-28 | — | — | CN | disclosed |
| CN-1217317-A | Fungicidal 2-methoxybenzophenones | AMERICAN CYANAMID CO (US) | 1999-05-26 | — | — | CN | disclosed |
| US-5306816-A | Processes for preparing carbapenem derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0280771-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0499196-A1 | Intermediates and process for preparing carbapenem derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-19 | — | — | EP | disclosed |
| US-5061804-A | 3-thiopyrrolidine as chemical intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-4963543-A | BACTERICIDES, TREATING INFECTIOUS DISEASES; THIENAMYCINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0280771-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |