⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16637278 | 0.79 | — | — | |
| SCHEMBL5985870 | 0.76 | — | — | |
| SCHEMBL7631910 | 0.73 | — | — | |
| SCHEMBL39152 | 0.72 | — | — | |
| SCHEMBL448834 | 0.72 | — | — | |
| SCHEMBL5605741 | 0.72 | — | — | |
| SCHEMBL269953 | 0.71 | — | — | |
| SCHEMBL271364 | 0.71 | — | — | |
| SCHEMBL5984610 | 0.69 | — | — | |
| SCHEMBL56024 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4956374-A | BACTERICIDES, CANDIDA | BRISTOL-MYERS COMPANY (US) | 1990-09-11 | — | — | US | claimed |
| US-20230053411-A1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-02-23 | — | — | US | disclosed |
| CN-110256418-B | 1, 3-thiazol-2-yl substituted benzamides | 拜耳公司 | 2023-01-20 | — | — | CN | disclosed |
| US-11142523-B2 | 1,3-thiazol-2-yl substituted benzamides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-10-12 | — | — | US | disclosed |
| US-20210220357-A1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES FOR THE TREATMENT OF DISEASES ASSOCIATED WITH NERVE FIBER SENSITIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 2021-07-22 | — | — | US | disclosed |
| US-20210220358-A1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES FOR THE TREATMENT OF DISEASES ASSOCIATED WITH NERVE FIBER SENSITIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 2021-07-22 | — | — | US | disclosed |
| EP-3793553-A1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES FOR THE TREATMENT OF DISEASES ASSOCIATED WITH NERVE FIBER SENSITIZATION | Bayer Aktiengesellschaft (DE) | 2021-03-24 | — | — | EP | disclosed |
| EP-3793554-A1 | 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES FOR THE TREATMENT OF DISEASES ASSOCIATED WITH NERVE FIBER SENSITIZATION | Bayer Aktiengesellschaft (DE) | 2021-03-24 | — | — | EP | disclosed |
| CN-112384213-A | 1, 3-thiazol-2-yl substituted benzamides for the treatment of diseases associated with nerve fiber sensitization | 拜耳公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-112334132-A | 1, 3-thiazol-2-yl substituted benzamides for the treatment of diseases associated with nerve fiber sensitization | 拜耳公司 | 2021-02-05 | — | — | CN | disclosed |
| WO-2007134984-A1 | HETEROAROYL-SUBSTITUTED ALANINES WITH A HERBICIDAL ACTION | BASF SE (DE) | 2007-11-29 | — | — | WO | disclosed |
| EP-1860503-A2 | Colored photosensitive resin composition, color filter, image sensor, and camera system | Sumitomo Chemical Company, Limited (JP) | 2007-11-28 | — | — | EP | disclosed |
| WO-2007093529-A2 | HETEROAROYL-SUBSTITUTED ALANINES | BASF SE (DE) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007093539-A2 | BENZOYL-SUBSTITUTED ALANINES | BASF SE (DE) | 2007-08-23 | — | — | WO | disclosed |
| WO-2006125688-A1 | BENZOYL-SUBSTITUTED SERINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | disclosed |
| WO-2006125687-A1 | HETEROAROYL-SUBSTITUTED SERINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | disclosed |
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |
| US-4956374-A | BACTERICIDES, CANDIDA | BRISTOL-MYERS COMPANY (US) | 1990-09-11 | — | — | US | disclosed |