Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261707 | 0.84 | HDAC3 (0.45) | MAPTNPC1HSD17B10KMT2AKDM4E | |
| SCHEMBL26905278 | 0.78 | MAPT (0.55) | MAPTNPC1HSD17B10KMT2AKDM4E | |
| SCHEMBL17380794 | 0.78 | KDM4E (0.38) | MAPTNPC1HSD17B10KMT2AKDM4E | |
| SCHEMBL26905281 | 0.77 | MAPT (0.54) | MAPTNPC1HSD17B10KMT2AKDM4E | |
| SCHEMBL16841248 | 0.76 | MEN1 (0.62) | MAPTNPC1HSD17B10KMT2AKDM4E | |
| SCHEMBL26905284 | 0.76 | MAPT (0.62) | MAPTNPC1HSD17B10KMT2AKDM4E | |
| SCHEMBL26905312 | 0.76 | MAPT (0.69) | MAPTNPC1HSD17B10KMT2AKDM4E | |
| SCHEMBL29722878 | 0.76 | MAPT (0.69) | MAPTNPC1HSD17B10KMT2AKDM4E | |
| SCHEMBL26905244 | 0.75 | MAPT (0.52) | MAPTNPC1HSD17B10KMT2AKDM4E | |
| SCHEMBL17943312 | 0.74 | KMT2A (0.60) | MAPTNPC1HSD17B10KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240131356-A1 | COMBINATION OF INTRACELLULAR AND EXTRACELLULAR PHOTOSENSITIZERS FOR TREATMENT OF BACTERIAL INFECTION | VANDERBILT UNIVERSITY | 2024-04-25 | — | — | US | disclosed |
| EP-4284912-A1 | COMBINATION OF INTRACELLULAR AND EXTRACELLULAR PHOTOSENSITIZERS FOR TREATMENT OF BACTERIAL INFECTION | Vanderbilt University (US) | 2023-12-06 | — | — | EP | disclosed |
| WO-2022165023-A1 | COMBINATION OF INTRACELLULAR AND EXTRACELLULAR PHOTOSENSITIZERS FOR TREATMENT OF BACTERIAL INFECTION | VANDERBILT UNIVERSITY (US) | 2022-08-04 | — | — | WO | disclosed |