⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30732609 | 0.75 | NPSR1 (0.31) | — | |
| SCHEMBL28666357 | 0.75 | — | — | |
| SCHEMBL8910802 | 0.73 | CYP2C19 (0.31) | — | |
| SCHEMBL28113416 | 0.70 | FFAR3 (0.31) | — | |
| SCHEMBL2789395 | 0.70 | FFAR3 (0.31) | — | |
| SCHEMBL22076456 | 0.69 | MEN1 (0.31) | — | |
| SCHEMBL21011643 | 0.66 | — | — | |
| SCHEMBL28723342 | 0.66 | PPM1D (0.31) | — | |
| SCHEMBL5381212 | 0.65 | — | — | |
| SCHEMBL31233121 | 0.65 | AKR1C1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284801-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | Janssen Biotech, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |
| WO-2022165529-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | JANSSEN BIOTECH, INC. (US) | 2022-08-04 | — | — | WO | disclosed |