⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15273680 | 0.78 | HPGD (0.38) | — | |
| SCHEMBL16110978 | 0.76 | — | — | |
| SCHEMBL24526739 | 0.76 | HPGD (0.39) | — | |
| SCHEMBL23399914 | 0.76 | — | — | |
| SCHEMBL6913389 | 0.74 | — | — | |
| SCHEMBL24828654 | 0.74 | — | — | |
| SCHEMBL15273691 | 0.74 | HPGD (0.35) | — | |
| SCHEMBL23400969 | 0.74 | HTT (0.38) | — | |
| SCHEMBL25107810 | 0.74 | KMT2A (0.38) | — | |
| SCHEMBL25108338 | 0.71 | HTT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174662-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | CILAG AG (CH) | 2024-05-30 | — | — | US | disclosed |
| EP-4284802-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | Janssen Biotech, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |
| WO-2022165530-A1 | SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES | JANSSEN BIOTECH, INC. (US) | 2022-08-04 | — | — | WO | disclosed |