SCHEMBL26907360

SCHEMBL26907360

Cn1ncc(O[C@@H]2CN(C(=O)O)C[C@H]2O)c1Br

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26907156 0.87 PIK3CD (0.31) PIK3CD
SCHEMBL26907791 0.87 PIK3CD (0.31) PIK3CD
SCHEMBL29770663 0.84 PIK3CD (0.43) PIK3CD
SCHEMBL29770638 0.84 PIK3CD (0.43) PIK3CD
SCHEMBL26907472 0.75 EGFR (0.36)
SCHEMBL29770732 0.72 USP30 (0.45) PIK3CD
SCHEMBL29770725 0.72 USP30 (0.45) PIK3CD
SCHEMBL29770829 0.72 USP30 (0.45) PIK3CD
SCHEMBL29770707 0.72 USP30 (0.45) PIK3CD
SCHEMBL26907577 0.72 USP30 (0.45) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240174662-A1 SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES CILAG AG (CH) 2024-05-30 US disclosed
EP-4284802-A1 SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES Janssen Biotech, Inc. (US) 2023-12-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174662-A1 SMALL MOLECULE INHIBITORS OF SALT INDUCIBLE KINASES SIK2, SIK1, SGK2 PIK3CD 389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.