Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 20/20 | 0.82 |
| ▸ | LPAR1 | Q92633 | 12/20 | 0.82 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.70 |
| ▸ | TSPO | P30536 | 1/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.70 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.70 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.70 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.70 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936115 | 1.00 | LPAR2 (0.82) | LPAR2LPAR1ADRB3TSPODRD3 | |
| SCHEMBL27116589 | 1.00 | LPAR2 (0.82) | LPAR2LPAR1ADRB3TSPODRD3 | |
| SCHEMBL26907286 | 0.85 | LPAR2 (1.00) | LPAR2LPAR1ADRB3TSPODRD3 | |
| SCHEMBL29936294 | 0.85 | LPAR2 (1.00) | LPAR2LPAR1ADRB3TSPODRD3 | |
| SCHEMBL29936112 | 0.83 | LPAR2 (0.86) | LPAR2LPAR1ADRB3TSPODRD3 | |
| SCHEMBL26907573 | 0.83 | LPAR2 (0.86) | LPAR2LPAR1ADRB3TSPODRD3 | |
| SCHEMBL23607009 | 0.82 | LPAR2 (1.00) | LPAR2LPAR1ADRB3TSPODRD3 | |
| SCHEMBL29936030 | 0.81 | LPAR2 (0.79) | LPAR2LPAR1ADRB3TSPODRD3 | |
| SCHEMBL29936262 | 0.81 | LPAR2 (0.79) | LPAR2LPAR1ADRB3TSPODRD3 | |
| SCHEMBL27116509 | 0.81 | LPAR2 (0.79) | LPAR2LPAR1ADRB3TSPODRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073073-B1 | THIENOPYRIMIDINE DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS | CHIESI FARM SPA (IT) | 2023-12-06 | — | — | EP | claimed |