⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27395585 | 0.98 | KDM4E (0.53) | — | |
| Ethyne SCHEMBL27709832 | 0.96 | KDM4E (0.52) | — | |
| SCHEMBL12277038 | 0.80 | — | — | |
| SCHEMBL28904171 | 0.80 | KDM4E (0.47) | — | |
| SCHEMBL28230831 | 0.79 | — | — | |
| SCHEMBL1341049 | 0.79 | — | — | |
| SCHEMBL6965578 | 0.79 | — | — | |
| SCHEMBL28135845 | 0.79 | — | — | |
| SCHEMBL29484249 | 0.79 | KDM4E (0.50) | — | |
| SCHEMBL243257 | 0.79 | MAPT (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482511-A2 | COMPOSITIONS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS | The Regents of The University of Michigan (US) | 2025-01-01 | — | — | EP | claimed |
| WO-2023164476-A2 | COMPOSITIONS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-08-31 | — | — | WO | claimed |
| EP-4216988-A1 | COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING AUTOIMMUNE DISORDERS | The Regents Of The University Of Michigan (US) | 2023-08-02 | — | — | EP | claimed |
| CN-112384204-B | Tolerogenic liposomes and methods of use thereof | 安托瑞斯公司 | 2023-03-14 | — | — | CN | claimed |
| WO-2022066825-A1 | COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING AUTOIMMUNE DISORDERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-03-31 | — | — | WO | claimed |
| CN-109574953-A | A kind of preparation method of 4-thiazolecarboxylic acid | 江苏诺恩作物科学股份有限公司 | 2019-04-05 | — | — | CN | claimed |
| US-7687490-B2 | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2010-03-30 | — | — | US | claimed |
| CN-101193891-A | 2-thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA (JP) | 2008-06-04 | — | — | CN | claimed |
| EP-1870412-A1 | 2-THIOETHENYL CARBAPENEM DERIVATIVE | MEIJI SEIKA KAISHA LTD. (JP) | 2007-12-26 | — | — | EP | claimed |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-01-04 | — | — | US | claimed |
| EP-4704867-A1 | METHODS OF DOSING AND ADMINISTRATION OF ENGINEERED ISLET CELLS | Sana Biotechnology, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| CN-120152713-A | Tricyclic aryl derivatives and compositions and methods thereof | 昂胜医疗科技公司 | 2025-06-13 | — | — | CN | disclosed |
| EP-4482511-A2 | COMPOSITIONS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS | The Regents of The University of Michigan (US) | 2025-01-01 | — | — | EP | disclosed |
| WO-2024229302-A1 | METHODS OF DOSING AND ADMINISTRATION OF ENGINEERED ISLET CELLS | SANA BIOTECHNOLOGY, INC. (US) | 2024-11-07 | — | — | WO | disclosed |
| CN-118284604-A | Fused heterocycles as RIPK1 inhibitors | 比西切姆有限公司 | 2024-07-02 | — | — | CN | disclosed |
| EP-1202990-A2 | NEUROTROPHIC PYRROLIDINES AND PIPERIDINES, AND RELATED COMPOSITIONS CONTAINING THEM | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-05-08 | — | — | EP | disclosed |
| CN-1080720-C | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 2002-03-13 | — | — | CN | disclosed |
| WO-2001004116-A2 | NEUROTROPHIC PYRROLIDINES AND PIPERIDINES, AND RELATED COMPOSITIONS CONTAINING THEM | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |
| CN-1261357-A | Process for preparing 2-hydroxybenzamide derivatives | ZERIA PHARM CO LTD (JP) | 2000-07-26 | — | — | CN | disclosed |
| CN-1224718-A | Thiazole derivatives | HOFFMANN LA ROCHE (CH) | 1999-08-04 | — | — | CN | disclosed |