⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014952 | 0.84 | TSHR (0.32) | — | |
| SCHEMBL29022796 | 0.79 | — | — | |
| SCHEMBL3388764 | 0.79 | — | — | |
| SCHEMBL622233 | 0.76 | — | — | |
| SCHEMBL6133077 | 0.73 | — | — | |
| SCHEMBL9548224 | 0.73 | — | — | |
| SCHEMBL6440318 | 0.73 | — | — | |
| SCHEMBL8436577 | 0.73 | — | — | |
| SCHEMBL28431395 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL4621221 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888338-B2 | 7-(2-cyclohexylidene-ethylidene)-spiro[4.5]decanes | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2011-02-15 | — | — | US | claimed |
| US-20060178350-A1 | 7-(2-Cyclohexylidene-ethylidene)-spiro[4.5]decanes | UNIVERSITEIT GENT (BE) | 2006-08-10 | — | — | US | claimed |
| WO-2006060884-A1 | 7-(2-CYCLOHEXYLIDENE-ETHYLIDENE)-SPIRO[4.5]DECANES | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2006-06-15 | — | — | WO | claimed |
| CN-111039774-A | Process for producing aliphatic carboxylic acid compound and pyridine compound adduct of aliphatic ketone compound | 捷恩智株式会社 | 2020-04-21 | — | — | CN | disclosed |
| WO-2014108526-A1 | SYNTHETIC PROCESS FOR THE MANUFACTURE OF PIPECOLIDEPSIN COMPOUNDS | PHARMA MAR, S.A. (ES) | 2014-07-17 | — | — | WO | disclosed |
| US-8633154-B2 | Cyclodepsipeptides with antineoplastic activity and methods of using to inhibit cancer and microbial growth | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2014-01-21 | — | — | US | disclosed |
| US-20130184201-A1 | Cyclodepsipeptides with Antineoplastic Activity and Methods of Using to Inhibit Cancer and Microbial Growth | ARIZONA STATE UNIVERSITY (US) | 2013-07-18 | — | — | US | disclosed |
| EP-1888509-B1 | BENZOYL-SUBSTITUTED SERINE AMIDES | BASF SE (DE) | 2013-05-15 | — | — | EP | disclosed |
| US-8415294-B2 | Cyclodepsipeptides with antineoplastic activity and methods of using to inhibit cancer and microbial growth | ARIZONA BOARD OF REGENTS (US) | 2013-04-09 | — | — | US | disclosed |
| US-8133851-B2 | Heteroaroyl-substituted serine amides | BASF SE (DE) | 2012-03-13 | — | — | US | disclosed |
| US-20110318470-A1 | Method For Improving Plant Health | BASF SE (DE) | 2011-12-29 | — | — | US | disclosed |
| EP-0332076-A2 | Cyclohexenone compounds, process for their preparation and their use in combating unwanted plant growth | BASF Aktiengesellschaft (DE) | 1989-09-13 | — | — | EP | disclosed |
| EP-0048614-B1 | 1-N-ACYLATED AND 1-N-ALKYLATED DERIVATIVES OF 4-0-SUBSTITUTED -2-DEOXYSTREPTAMINE AMINOGLYCOSIDES | ELI LILLY AND COMPANY (US) | 1985-03-20 | — | — | EP | disclosed |
| EP-0048613-B1 | 4-0-SUBSTITUTED -2-DEOXYSTREPTAMINE AMINOGLYCOSIDE DERIVATIVES, THEIR PREPARATION AND FORMULATIONS CONTAINING THEM | ELI LILLY AND COMPANY (US) | 1985-01-23 | — | — | EP | disclosed |
| US-4468512-A | 1-N-Acylated and 1-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| US-4468513-A | 2'-N-Acylated and 2'-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| US-4424344-A | 2-N-Acylated and 2-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides and process | ELI LILLY AND COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| US-4424345-A | 1-N-Acylated and 1-N-alkylated derivatives of 4-O-substituted-2-deoxystreptamine aminoglycosides and process | ELI LILLY AND COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| EP-0048614-A1 | 1-N-acylated and 1-N-alkylated derivatives of 4-0-substituted -2-deoxystreptamine aminoglycosides | ELI LILLY AND COMPANY (US) | 1982-03-31 | — | — | EP | disclosed |
| EP-0048613-A1 | 4-0-Substituted -2-deoxystreptamine aminoglycoside derivatives, their preparation and formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-31 | — | — | EP | disclosed |