Formic Acid

Formic Acid

SCHEMBL26918862

Cn1cnnc1[C@@H](F)C1(c2cccc(NC(=O)c3cc(CN)cc(C(F)(F)F)n3)c2)COC1.O=CO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.52
▸ CBLC Q9ULV8 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL26918818 1.00 CBLB (0.52) CBLBCBLC
Formic Acid SCHEMBL26918822 1.00 CBLB (0.52) CBLBCBLC
Formic Acid SCHEMBL29998582 1.00 CBLB (0.52) CBLBCBLC
Formic Acid SCHEMBL29998375 1.00 CBLB (0.52) CBLBCBLC
SCHEMBL26918677 0.87 CBLB (0.52) CBLBCBLC
SCHEMBL26918678 0.87 CBLB (0.52) CBLBCBLC
SCHEMBL29998415 0.87 CBLB (0.52) CBLBCBLC
SCHEMBL29998760 0.87 CBLB (0.52) CBLBCBLC
SCHEMBL31099543 0.80 CBLB (0.52) CBLBCBLC
SCHEMBL26918522 0.80 CBLB (0.52) CBLBCBLC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288428-A1 AMIDES AS CBL-B INHIBITORS Genentech, Inc. (US) 2023-12-13 — — EP claimed
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