Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 20/20 | 0.64 |
| ▸ | CBLC | Q9ULV8 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29998756 | 1.00 | CBLB (0.64) | CBLBCBLC | |
| SCHEMBL29998537 | 1.00 | CBLB (0.64) | CBLBCBLC | |
| SCHEMBL26922723 | 1.00 | CBLB (0.64) | CBLBCBLC | |
| SCHEMBL29997885 | 0.90 | CBLB (0.66) | CBLBCBLC | |
| SCHEMBL26918640 | 0.90 | CBLB (0.66) | CBLBCBLC | |
| SCHEMBL26918641 | 0.90 | CBLB (0.66) | CBLBCBLC | |
| SCHEMBL29998646 | 0.90 | CBLB (0.66) | CBLBCBLC | |
| SCHEMBL31099536 | 0.89 | CBLB (0.52) | CBLBCBLC | |
| SCHEMBL31099532 | 0.89 | CBLB (0.52) | CBLBCBLC | |
| SCHEMBL29998886 | 0.86 | CBLB (0.55) | CBLBCBLC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288428-A1 | AMIDES AS CBL-B INHIBITORS | Genentech, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |