Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GRM5 | P41594 | 4/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26923549 | 1.00 | GAA (0.49) | GAALMNAGRM5FPR2KDM4E | |
| SCHEMBL30599125 | 1.00 | GAA (0.49) | GAALMNAGRM5FPR2KDM4E | |
| SCHEMBL31231767 | 0.88 | GAA (0.48) | GAALMNAGRM5FPR2KDM4E | |
| SCHEMBL30714528 | 0.88 | GAA (0.48) | GAALMNAGRM5FPR2KDM4E | |
| SCHEMBL30599079 | 0.88 | GAA (0.48) | GAALMNAGRM5FPR2KDM4E | |
| SCHEMBL26252140 | 0.88 | GAA (0.48) | GAALMNAGRM5FPR2KDM4E | |
| SCHEMBL31415247 | 0.85 | GAA (0.49) | GAALMNAGRM5FPR2KDM4E | |
| SCHEMBL31415270 | 0.85 | GAA (0.49) | GAALMNAGRM5FPR2KDM4E | |
| SCHEMBL1840355 | 0.82 | GAA (0.60) | GAALMNAGRM5FPR2KDM4E | |
| SCHEMBL31284421 | 0.81 | GRM5 (0.43) | GAALMNAGRM5FPR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240084-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | disclosed |