Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 12/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.50 |
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26924926 | 1.00 | DDB1 (0.50) | DDB1CRBNIKZF2 | |
| SCHEMBL26925357 | 1.00 | DDB1 (0.50) | DDB1CRBNIKZF2 | |
| SCHEMBL26924933 | 1.00 | DDB1 (0.50) | DDB1CRBNIKZF2 | |
| SCHEMBL30731962 | 0.91 | DDB1 (0.61) | DDB1CRBN | |
| SCHEMBL30732165 | 0.91 | DDB1 (0.61) | DDB1CRBN | |
| SCHEMBL30732319 | 0.91 | DDB1 (0.61) | DDB1CRBN | |
| SCHEMBL30731940 | 0.91 | DDB1 (0.61) | DDB1CRBN | |
| SCHEMBL26924626 | 0.88 | CRBN (0.50) | DDB1CRBN | |
| SCHEMBL26924739 | 0.88 | CRBN (0.50) | DDB1CRBN | |
| SCHEMBL26925366 | 0.88 | CRBN (0.50) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240038-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |