Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 11/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 11/20 | 0.48 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30204284 | 0.82 | PARP1 (0.50) | PARP1 | |
| Hydrochloric Acid SCHEMBL28482415 | 0.81 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL12849554 | 0.80 | USP30 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL665549 | 0.79 | PARP1 (0.57) | PARP1 | |
| SCHEMBL663560 | 0.79 | PARP1 (0.57) | PARP1 | |
| SCHEMBL12890049 | 0.79 | PARP1 (0.57) | PARP1 | |
| SCHEMBL30204431 | 0.79 | PARP1 (0.51) | PARP1ALDH1A1 | |
| SCHEMBL15692075 | 0.79 | PARP1 (0.48) | HCRTR1HCRTR2PARP1ALDH1A1 | |
| SCHEMBL30204221 | 0.77 | PARP1 (0.46) | PARP1ALDH1A1 | |
| SCHEMBL12061793 | 0.75 | NPC1 (0.60) | HCRTR1HCRTR2PARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289834-A1 | TETRAHYDROPYRROLOCYCLIC COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2023-12-13 | — | — | EP | disclosed |