Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 17/20 | 0.45 |
| ▸ | SRC | P12931 | 8/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.43 |
| ▸ | HCK | P08631 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29662330 | 1.00 | BRAF (0.45) | BRAFSRCMAPK12MAPK14HCK | |
| SCHEMBL26935844 | 0.84 | BRAF (0.38) | BRAFSRCMAPK12MAPK14HCK | |
| SCHEMBL29662185 | 0.82 | BRAF (0.45) | BRAF | |
| SCHEMBL26947521 | 0.82 | BRAF (0.45) | BRAF | |
| SCHEMBL28697170 | 0.80 | HCK (0.64) | BRAFSRCMAPK12MAPK14HCK | |
| SCHEMBL29662269 | 0.80 | BRAF (0.49) | BRAFSRCMAPK12MAPK14HCK | |
| SCHEMBL26947537 | 0.80 | BRAF (0.49) | BRAFSRCMAPK12MAPK14HCK | |
| SCHEMBL26937722 | 0.77 | BRAF (0.44) | BRAF | |
| SCHEMBL28933349 | 0.74 | MAPK14 (0.47) | SRCMAPK12MAPK14 | |
| SCHEMBL28933411 | 0.72 | MAPK14 (0.51) | SRCMAPK12MAPK14HCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | claimed |
| WO-2023237759-A1 | DIHYDRO[1,8]NAPHTHYRIDIN-7-ONE AND PYRIDO[3,2-B][1,4]OXAZIN-3-ONE FOR USE IN TREATING CANCER, AND METASTASES IN PARTICULAR | ANAGENESIS BIOTECHNOLOGIES (FR) | 2023-12-14 | — | — | WO | disclosed |
| EP-4289427-A1 | DIHYDRO[1,8]NAPHTHYRIDIN-7-ONE AND PYRIDO[3,2-B][1,4]OXAZIN-3-ONE FOR USE IN TREATING CANCER, AND METASTASES IN PARTICULAR. | Anagenesis Biotechnologies (FR) | 2023-12-13 | — | — | EP | disclosed |
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |