SCHEMBL2694035

SCHEMBL2694035

NCCCC[C@H](N)C(=O)N1CCCC1

nearest known ligand 0.64

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 16/20 0.64
DPP4 P27487 6/20 0.64
DPP8 Q6V1X1 6/20 0.64
DPP9 Q86TI2 6/20 0.64
FAP Q12884 1/20 0.54
ITGB3 P05106 2/20 0.53
ITGA2B P08514 2/20 0.53
GSR P00390 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29049118 1.00 DPP7 (0.64) DPP7DPP4DPP8DPP9FAP
SCHEMBL6752685 0.98 DPP7 (0.62) DPP7DPP4DPP8DPP9FAP
SCHEMBL6823994 0.93 DPP7 (0.61) DPP7DPP4DPP8DPP9FAP
Trifluoroacetic Acid SCHEMBL6820916 0.89 DPP7 (0.54) DPP7DPP4DPP8DPP9FAP
Trifluoroacetic Acid SCHEMBL6826306 0.88 DPP7 (0.52) DPP7DPP4DPP8DPP9FAP
Trifluoroacetic Acid SCHEMBL6820622 0.88 DPP7 (0.52) DPP7DPP4DPP8DPP9FAP
Trifluoroacetic Acid SCHEMBL6826315 0.86 DPP7 (0.54) DPP7DPP4DPP8DPP9FAP
SCHEMBL1063047 0.85 DPP7 (0.59) DPP7DPP4DPP8DPP9FAP
SCHEMBL1063045 0.85 DPP7 (0.59) DPP7DPP4DPP8DPP9FAP
SCHEMBL6820919 0.85 DPP7 (0.59) DPP7DPP4DPP8DPP9FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024143263-A1 FLUORESCENCE INTENSITY ENHANCING AGENT, METHOD FOR ENHANCING FLUORESCENCE INTENSITY OF FLUORESCENTLY LABELED TARGET BIOLOGICAL MATERIAL, AND FLUORESCENCE DETECTION KIT 富士フイルム株式会社 2024-07-04 WO disclosed
CN-116359195-A Heme saccharification end product detection instrument and detection container thereof 晶铄科技有限公司 2023-06-30 CN disclosed
EP-3168288-B1 FLUORESCENT PROBE FOR DETECTING DIPEPTIDYL PEPTIDASE IV UNIV TOKYO (JP) 2020-06-03 EP disclosed
US-8168199-B2 Dipeptidyl peptidase IV inhibitors for the treatment of schizophrenia and depression von Hoersten, Stephan (DE) 2012-05-01 US disclosed
US-20090062203-A1 DIPEPTIDYL PEPTIDASE IV INHIBITORS FOR THE TREATMENT OF SCHIZOPHRENIA AND DEPRESSION PROBIODRUG AG (DE) 2009-03-05 US disclosed
US-7435420-B2 Dipeptidyl peptidase IV inhibitors for the treatment of anxiety PROBIODRUG AG (DE) 2008-10-14 US disclosed
US-20060252701-A1 Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV)-like activity for the treatment of neurological and neuropsychological disorders PROBIODRUG 2006-11-09 US disclosed
US-7132104-B1 Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders PROBIODRUG AG (DE) 2006-11-07 US disclosed
EP-0490379-A2 Diamino acid derivatives and pharmaceutical compositions BERLIN-CHEMIE Aktiengesellschaft (DE) 1992-06-17 EP disclosed