Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 13/20 | 0.58 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.58 |
| ▸ | CCNK | O75909 | 2/20 | 0.58 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.58 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.46 |
| ▸ | CDK1 | P06493 | 5/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.46 |
| ▸ | CCR6 | P51684 | 2/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.45 |
| ▸ | MERTK | Q12866 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.44 |
| ▸ | CDK4 | P11802 | 3/20 | 0.44 |
| ▸ | CCND1 | P24385 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26942670 | 1.00 | CDK2 (0.58) | CDK2CCNA2CCNKCDK12SYK | |
| SCHEMBL26942168 | 1.00 | CDK2 (0.58) | CDK2CCNA2CCNKCDK12SYK | |
| SCHEMBL26942674 | 1.00 | CDK2 (0.58) | CDK2CCNA2CCNKCDK12SYK | |
| SCHEMBL26942170 | 1.00 | CDK2 (0.58) | CDK2CCNA2CCNKCDK12SYK | |
| SCHEMBL26942075 | 0.91 | CDK2 (0.52) | CDK2CCNA2CCNKCDK12SYK | |
| SCHEMBL26941649 | 0.91 | CDK2 (0.52) | CDK2CCNA2CCNKCDK12SYK | |
| SCHEMBL26944562 | 0.91 | CDK2 (0.52) | CDK2CCNA2CCNKCDK12SYK | |
| SCHEMBL26941594 | 0.91 | CDK2 (0.52) | CDK2CCNA2CCNKCDK12SYK | |
| SCHEMBL26942059 | 0.90 | CDK2 (0.63) | CDK2CCNA2CCNKCDK12CCNE1 | |
| SCHEMBL26942397 | 0.86 | CDK2 (0.52) | CDK2CCNA2CCNKCDK12SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |