Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 8/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.37 |
| ▸ | CDK1 | P06493 | 3/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 4/20 | 0.36 |
| ▸ | CCNH | P51946 | 4/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.36 |
| ▸ | CDK9 | P50750 | 3/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | CCND3 | P30281 | 2/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.36 |
| ▸ | IKBKB | O14920 | 5/20 | 0.35 |
| ▸ | CCNK | O75909 | 3/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26943396 | 0.93 | CDK2 (0.39) | TRPV1CDK2KDRCCNE1CDK1 | |
| SCHEMBL26943984 | 0.92 | LRRK2 (0.44) | TRPV1CDK2KDRCCNE1CDK1 | |
| Hydrochloric Acid SCHEMBL29763104 | 0.91 | IKBKB (0.42) | TRPV1CDK2KDRCCNE1CDK1 | |
| Hydrochloric Acid SCHEMBL26918989 | 0.91 | IKBKB (0.42) | TRPV1CDK2KDRCCNE1CDK1 | |
| Hydrochloric Acid SCHEMBL26918985 | 0.91 | IKBKB (0.42) | TRPV1CDK2KDRCCNE1CDK1 | |
| SCHEMBL26919405 | 0.91 | IKBKB (0.43) | TRPV1CDK2KDRCCNE1CDK1 | |
| SCHEMBL29763024 | 0.91 | IKBKB (0.43) | TRPV1CDK2KDRCCNE1CDK1 | |
| SCHEMBL26919395 | 0.91 | IKBKB (0.43) | TRPV1CDK2KDRCCNE1CDK1 | |
| SCHEMBL26943306 | 0.86 | IKBKB (0.42) | TRPV1CDK2KDRCCNE1CDK1 | |
| SCHEMBL26946820 | 0.84 | IKBKB (0.41) | TRPV1CDK2KDRCCNE1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289835-A1 | CDK INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |