Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22586963 | 0.88 | KRAS (0.52) | KRAS | |
| SCHEMBL27117434 | 0.87 | KRAS (0.51) | KRAS | |
| SCHEMBL22220480 | 0.86 | KRAS (0.61) | KRAS | |
| SCHEMBL22220169 | 0.85 | KRAS (0.77) | KRAS | |
| SCHEMBL22220709 | 0.85 | KRAS (0.77) | KRAS | |
| SCHEMBL30064960 | 0.85 | KRAS (0.77) | KRAS | |
| SCHEMBL26947411 | 0.85 | KRAS (0.77) | KRAS | |
| SCHEMBL30064906 | 0.85 | KRAS (0.77) | KRAS | |
| SCHEMBL26932676 | 0.85 | KRAS (0.77) | KRAS | |
| SCHEMBL30064886 | 0.85 | KRAS (0.71) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240188-A1 | PYRIDO[4,3-D]PYRIMIDINE DERIVATIVES AS KRAS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-12-14 | — | — | WO | disclosed |