Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26951789 | 0.81 | NPC1 (0.43) | PCSK9KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL26953421 | 0.78 | NPC1 (0.41) | PCSK9KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL26240140 | 0.78 | PCSK9 (0.41) | PCSK9KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL23791702 | 0.78 | NPC1 (0.42) | PCSK9KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL26239675 | 0.74 | PCSK9 (0.41) | PCSK9KDM4EALDH1A1CYP1A2HPGD | |
| SCHEMBL27446444 | 0.73 | HRH3 (0.37) | KDM4EALDH1A1ALOX5AP | |
| SCHEMBL24155606 | 0.71 | NPC1 (0.48) | ALDH1A1CYP1A2NPC1GBA1RAB9A | |
| SCHEMBL15044971 | 0.70 | LCK (0.41) | ALDH1A1CYP1A2HPGDNPC1RAB9A | |
| SCHEMBL2101505 | 0.70 | AURKA (0.56) | KDM4EALDH1A1CYP1A2HPGDNPC1 | |
| SCHEMBL25763723 | 0.69 | CYP2A6 (0.47) | HPGDNPC1RAB9AATMALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289833-A1 | TYK2 INHIBITOR COMPOUND CONTAINING BICYCLIC RING | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-12-13 | — | — | EP | disclosed |