Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 4/20 | 0.54 |
| ▸ | CES1 | P23141 | 4/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL6706070 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Octanoic Acid SCHEMBL18420326 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Stearic Acid SCHEMBL8398074 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL673494 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Octanoic Acid SCHEMBL2570134 | 1.00 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL1115521 | 0.98 | FABP3 (0.58) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL10558070 | 0.98 | FABP3 (0.58) | FABP3CA1CES2CES1NFKB1 | |
| Octanoic Acid SCHEMBL5171291 | 0.96 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Palmitic Acid SCHEMBL27958546 | 0.96 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL394257 | 0.96 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168700-B2 | Electrodepositable coating compositions and related methods | PPG INDUSTRIES OHIO, INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-20090111916-A1 | ELECTRODEPOSITABLE COATING COMPOSITIONS AND RELATED METHODS | PPG INDUSTRIES OHIO, INC,. (US) | 2009-04-30 | — | — | US | disclosed |
| US-6124380-A | Metal containing e-coat catalysts optionally with tin catalysts | ELF ATOCHEM NORTH AMERICA, INC. (US) | 2000-09-26 | — | — | US | disclosed |
| US-6042893-A | ELECTRODEPOSITION OF CURABLE CATIONIC POLYMER ONTO ELECTROCONDUCTIVE SUBSTRATE IMMERSED IN BATH CONTAINING RESIN AND ORGANOMETALLIC POLYMERIZATION CATALYST MIXTURE | ELF ATOCHEM NORTH AMERICA INC. (US) | 2000-03-28 | — | — | US | disclosed |
| US-6028128-A | Metal containing E-coat catalysts optionally with tin catalysts | ELF ATOCHEM NORTH AMERICA, INC. (US) | 2000-02-22 | — | — | US | disclosed |
| US-6001900-A | CURABLE COATING WITH BLOCKED ISOCYANATE OR BLOCKED ISOTHIOCYANATE AND ACTIVE HYDROGEN COMPOUND AND REACTION OF ORGANOTIN COMPOUND | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1999-12-14 | — | — | US | disclosed |
| US-5910373-A | PROMOTION OF LOW TEMPERATURE CURE OF BLOCKED ISOCYANATES AND BLOCKED ISOTHIOCYANATES | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1999-06-08 | — | — | US | disclosed |
| US-5859165-A | FOR PROMOTING THE REACTION OF A REACTIVE COMPONENT WITH A BLOCKED ISOCYANATE COMPRISING THE REACTION PRODUCT OF A METAL CATALYST, A TRIORGANOTIN COMPOUND AND A MERCAPTAN | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1999-01-12 | — | — | US | disclosed |