Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 11/20 | 0.44 |
| ▸ | BRAF | P15056 | 3/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | CLK2 | P49760 | 3/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | PAK4 | O96013 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | LTK | P29376 | 2/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31735040 | 1.00 | LRRK2 (0.44) | LRRK2BRAFPRKD3MAP4K4MAPK8 | |
| SCHEMBL4792269 | 0.82 | LRRK2 (0.58) | LRRK2BRAFPRKD3MAP4K4MAPK8 | |
| SCHEMBL4790325 | 0.82 | LRRK2 (0.61) | LRRK2BRAFPRKD3MAP4K4MAPK8 | |
| SCHEMBL26953049 | 0.81 | LRRK2 (0.44) | LRRK2BRAFPRKD3MAP4K4MAPK8 | |
| SCHEMBL26953024 | 0.78 | IKBKB (0.64) | LRRK2PRKD3MAP4K4MAPK8CLK2 | |
| SCHEMBL31734974 | 0.78 | IKBKB (0.64) | LRRK2PRKD3MAP4K4MAPK8CLK2 | |
| SCHEMBL26953090 | 0.71 | LRRK2 (0.49) | LRRK2PRKD3MAP4K4MAPK8CLK2 | |
| SCHEMBL31734980 | 0.71 | LRRK2 (0.49) | LRRK2PRKD3MAP4K4MAPK8CLK2 | |
| SCHEMBL4793527 | 0.69 | LRRK2 (0.48) | LRRK2BRAFPRKD3MAP4K4MAPK8 | |
| SCHEMBL31734967 | 0.68 | LRRK2 (0.46) | LRRK2PRKD3MAP4K4MAPK8CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239727-A1 | LATS INHIBITORS AND USES THEREOF | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-12-14 | — | — | WO | disclosed |