Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL720973 | 0.88 | — | — | |
| Methyl Alcohol SCHEMBL998584 | 0.87 | — | — | |
| SCHEMBL4950820 | 0.87 | TSHR (0.50) | — | |
| SCHEMBL3814841 | 0.87 | — | — | |
| SCHEMBL2430668 | 0.87 | TSHR (0.50) | — | |
| SCHEMBL10862 | 0.87 | — | — | |
| SCHEMBL5606390 | 0.87 | — | — | |
| SCHEMBL4901795 | 0.87 | TSHR (0.50) | — | |
| SCHEMBL9245377 | 0.83 | — | — | |
| Allyl Alcohol SCHEMBL2287551 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103254196-B | Preparation method of pemetrexed diacid | SUZHOU MIRACPHARMA TECHNOLOGY CO LTD | 2015-02-18 | — | — | CN | disclosed |
| US-8884062-B2 | Aminodihydrothiazine derivatives substituted with a cyclic group | SHIONOGI & CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| EP-2147914-B1 | AMINODIHYDROTHIAZINE DERIVATIVES SUBSTITUTED WITH CYCLIC GROUPS | SHIONOGI & CO (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-20140073815-A1 | AMINODIHYDROTHIAZINE DERIVATIVES SUBSTITUTED WITH A CYCLIC GROUP | SHIONOGI & CO., LTD. (JP) | 2014-03-13 | — | — | US | disclosed |
| EP-2689780-A1 | Intermediates for aminodihydrothiazine derivatives substituted with a cyclic group | SHIONOGI & CO., LTD. (JP) | 2014-01-29 | — | — | EP | disclosed |
| US-8541408-B2 | Aminodihydrothiazine derivatives substituted with a cyclic group | SHIONOGI & CO., LTD. (JP) | 2013-09-24 | — | — | US | disclosed |
| CN-103254196-A | Preparation method of pemetrexed diacid | SUZHOU MINGRUI MEDICAL TECHNOLOGY CO LTD | 2013-08-21 | — | — | CN | disclosed |
| US-8507479-B2 | — | — | 2013-08-13 | — | — | US | disclosed |
| US-20120172355-A1 | AMINODIHYDROTHIAZINE DERIVATIVES SUBSTITUTED WITH A CYCLIC GROUP | SHIONOGI & CO., LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
| US-8168630-B2 | Aminodihydrothiazine derivatives substituted with a cyclic group | SHIONOGI & CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-20100075957-A1 | AMINODIHYDROTHIAZINE DERIVATIVES SUBSTITUTED WITH A CYCLIC GROUP | SHIONOGI & CO., LTD. (JP) | 2010-03-25 | — | — | US | disclosed |
| EP-2147914-A1 | AMINODIHYDROTHIAZINE DERIVATIVES SUBSTITUTED WITH CYCLIC GROUPS | Shionogi&Co., Ltd. (JP) | 2010-01-27 | — | — | EP | disclosed |
| CN-100408439-C | Device for dispensing selected material to liquid and its mfg. method | BIOGAIA BIOLOG AB (SE) | 2008-08-06 | — | — | CN | disclosed |
| CN-1618705-A | Device for dispensing selected material to liquid and its mfg. method | BIOGAIA BIOLOG AB (SE) | 2005-05-25 | — | — | CN | disclosed |
| CN-1187012-C | Device for dispensing viable cells of a native microorganism into a liquid and method for producing the same | BIOGAIA BIOLOG AB (SE) | 2005-02-02 | — | — | CN | disclosed |
| CN-1374917-A | Distributing pipe | BIOGAIA BIOLOG AB (SE) | 2002-10-16 | — | — | CN | disclosed |