Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 1.00 |
| ▸ | EBP | Q15125 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5852043 | 0.93 | ESR1 (1.00) | ESR1EBPSIGMAR1ESR2 | |
| SCHEMBL2817611 | 0.93 | ESR1 (0.86) | ESR1EBPSIGMAR1ESR2CYP26A1 | |
| SCHEMBL5851662 | 0.89 | ESR1 (0.88) | ESR1ESR2 | |
| SCHEMBL5851639 | 0.88 | ESR1 (0.78) | ESR1EBPSIGMAR1ESR2 | |
| SCHEMBL23195741 | 0.88 | ESR1 (0.78) | ESR1EBPSIGMAR1ESR2 | |
| SCHEMBL7623247 | 0.86 | ESR1 (0.75) | ESR1EBPSIGMAR1ESR2CYP26A1 | |
| SCHEMBL3652303 | 0.86 | ESR1 (0.79) | ESR1ESR2 | |
| SCHEMBL11821605 | 0.84 | ESR1 (0.72) | ESR1EBPSIGMAR1CYP26A1MIF | |
| SCHEMBL5852025 | 0.84 | ESR1 (0.72) | ESR1EBPSIGMAR1 | |
| SCHEMBL3657155 | 0.82 | ESR1 (0.70) | ESR1ESR2CYP26A1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289841-A1 | BENZO SEVEN-MEMBERED RING BIFUNCTIONAL COMPOUND AND APPLICATION THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-12-13 | — | — | EP | disclosed |