Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26961788 | 0.95 | CNR2 (0.34) | CNR2NPY1RPOLBMAPTCCKBR | |
| SCHEMBL26961913 | 0.94 | CNR2 (0.34) | CNR2NPY1RPOLBMAPTCCKBR | |
| SCHEMBL26961678 | 0.94 | CNR2 (0.34) | CNR2NPY1RPOLBMAPTCCKBR | |
| SCHEMBL26961701 | 0.94 | CNR2 (0.34) | CNR2NPY1RPOLBMAPTCCKBR | |
| SCHEMBL26962268 | 0.93 | NPY1R (0.36) | CNR2NPY1RPOLBMAPTCCKBR | |
| SCHEMBL26961976 | 0.92 | CNR2 (0.33) | CNR2NPY1RPOLBMAPTCCKBR | |
| SCHEMBL26961674 | 0.89 | NPY1R (0.33) | CNR2NPY1RPOLBMAPTCCKBR | |
| SCHEMBL26962074 | 0.88 | CNR2 (0.31) | CNR2NPY1RPOLBMAPTXIAP | |
| SCHEMBL26961956 | 0.87 | NPY1R (0.33) | NPY1RPOLBMAPTCCKBRXIAP | |
| SCHEMBL26962112 | 0.87 | CNR2 (0.33) | CNR2NPY1RPOLBMAPTXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4291558-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2023-12-20 | — | — | EP | disclosed |