SCHEMBL269719

SCHEMBL269719

[CH2]CO[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1844750 0.67
SCHEMBL309726 0.59
SCHEMBL2487 0.59
SCHEMBL5981508 0.59
SCHEMBL10353958 0.59
SCHEMBL181037 0.59
SCHEMBL8764882 0.56
SCHEMBL8160485 0.56
SCHEMBL1592 0.56
SCHEMBL7907850 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0742223-B1 A method of preparing a derivative of optically active azetidin-2-one TAKASAGO PERFUMERY CO LTD (JP) 1999-11-17 EP claimed
US-5712388-A Method of preparing a derivative of optically active azetidin-2-one TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-01-27 US claimed
EP-0742223-A1 A method of preparing a derivative of optically active azetidin-2-one Takasago International Corporation (JP) 1996-11-13 EP claimed
WO-2024106539-A1 LIGAND CONJUGATE SUBSTANCE, NUCLEIC ACID CONTAINING SAME, AND USE THEREOF 株式会社ボナック 2024-05-23 WO disclosed
CN-117776585-A Hydrophobing agent for concrete and preparation method thereof 河北恒誉伟业建材有限公司 2024-03-29 CN disclosed
US-11771640-B2 Water-in-oil emulsion cosmetic SHISEIDO COMPANY, LTD. (JP) 2023-10-03 US disclosed
CN-115215621-B Method for preparing baking-free ceramsite from electroplating sludge 安徽美琛生态科技有限公司 2023-07-18 CN disclosed
US-20230183283-A1 NOVEL GLYCOSIDE COMPOUND AND PRODUCTION METHOD THEREFOR BONAC CORPORATION (JP) 2023-06-15 US disclosed
US-20230057927-A1 STABILIZING VITAMIN C TOPICAL FORMULATIONS MF BEAUTY PARTNERS LLC 2023-02-23 US disclosed
CN-115215621-A Method for preparing non-sintered ceramsite from electroplating sludge 安徽美琛生态科技有限公司 2022-10-21 CN disclosed
CN-112263706-B Biodegradable biological adhesive and preparation method thereof 苏州度博迈医疗科技有限公司 2022-05-13 CN disclosed
EP-0742223-B1 A method of preparing a derivative of optically active azetidin-2-one TAKASAGO PERFUMERY CO LTD (JP) 1999-11-17 EP disclosed
US-5986084-A NUCLEOSIDE WITH TRIPLE SUBSTITUTED SILYLOXYMETHYL GROUP AS A PROTECTION GROUP ON THE 2' OXYGEN; PROTECTION GROUPS ARE NOT SUBJECT TO ISOMERIZATION AND GIVE HIGHER COUPLING YIELDS QIAGEN AG (CH) 1999-11-16 US disclosed
US-5712388-A Method of preparing a derivative of optically active azetidin-2-one TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-01-27 US disclosed
EP-0742223-A1 A method of preparing a derivative of optically active azetidin-2-one Takasago International Corporation (JP) 1996-11-13 EP disclosed
CN-1065061-A Novel 4-substituted azetidinones as precursors to 2-substituted-3-carboxycarbapenem antibiotics and processes for their preparation AMERICAN CYANAMID CO (US) 1992-10-07 CN disclosed
EP-0481116-A1 A process for producing halomethylcarbapenems SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI &amp; CO. LTD. (JP) 1992-04-22 EP disclosed
US-5064954-A Phosphorylation of hydroxymethylcarbapem and halogenation; bactericides SHIONOGI & CO., LTD. (JP) 1991-11-12 US disclosed
US-4816578-A Process for the stereocontrolled silyloxyethylation of azetidinones MERCK & CO., INC. (US) 1989-03-28 US disclosed
EP-0211236-A1 7-Oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1987-02-25 EP disclosed