SCHEMBL26976

SCHEMBL26976

Cn1cnc2ncnc(N)c21

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 5/20 0.61
ADORA1 P30542 3/20 0.59
LIMK1 P53667 1/20 0.39
PI4KA P42356 4/20 0.36
PI4K2B Q8TCG2 4/20 0.36
PI4K2A Q9BTU6 4/20 0.36
PI4KB Q9UBF8 4/20 0.36
ADORA2B P29275 1/20 0.36
PIK3CD O00329 2/20 0.36
KDR P35968 6/20 0.36
LMNA P02545 1/20 0.35
DRD3 P35462 1/20 0.35
XDH P47989 1/20 0.35
LRRK2 Q5S007 1/20 0.35
EGFR P00533 1/20 0.35
SRC P12931 1/20 0.35
TEK Q02763 1/20 0.35
DNMT3A Q9Y6K1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23365318 0.81 ADORA2A (0.43) ADORA2AADORA1
SCHEMBL18076190 0.77 ADORA2A (0.56) ADORA2AADORA1LIMK1PI4KAPI4K2B
SCHEMBL946620 0.77 ADORA2A (0.56) ADORA2AADORA1LIMK1PI4KAPI4K2B
SCHEMBL24393386 0.77 ADORA2A (0.41) ADORA2AADORA1ADORA2BPIK3CDLMNA
SCHEMBL5355348 0.75 ADORA2A (0.40) ADORA2AADORA1ADORA2BPIK3CDLMNA
SCHEMBL15942468 0.75 ADORA2A (0.55) ADORA2AADORA1LIMK1PI4KAPI4K2B
SCHEMBL7040284 0.75 ADORA2A (0.40) ADORA2AADORA1ADORA2BPIK3CDLMNA
SCHEMBL946072 0.75 ADORA2A (0.55) ADORA2AADORA1LIMK1PI4KAPI4K2B
SCHEMBL12699730 0.75 ADORA2A (0.55) ADORA2AADORA1LIMK1PI4KAPI4K2B
SCHEMBL2414858 0.75 ADORA2A (0.40) ADORA2AADORA1ADORA2BPIK3CDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 19539 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
US-12630827-B2 Antisense oligonucleotides targeting SCN2A for the treatment of SCN1A encephalopathies ROGCON, INC. (US) 2026-05-19 US claimed
US-20260098287-A1 METHOD AND KIT FOR REGENERATING REUSABLE INITIATORS FOR NUCLEIC ACID SYNTHESIS CHENG-YAO CHEN (TW) 2026-04-09 US claimed
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 EP claimed
US-20250345406-A1 CHIMERIC PROTEINS IN AUTOIMMUNITY SHATTUCK LABS INC (US) 2025-11-13 US claimed
US-20250325494-A1 COMPOSITION FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACID THEMEDIUM THERAPEUTICS CO., LTD. (CN) 2025-10-23 US claimed
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 EP claimed
EP-4630009-A1 ANTISENSE RNA (ASRNA) TECHNOLOGY AND USE THEREOF 1Globe Health Institute LLC (US) 2025-10-15 EP claimed
EP-4630008-A1 SHORT DUPLEX RNA WITH INTERSPERSED DEOXYRIBONUCLEOTIDES AS A GENE SILENCING TECHNOLOGY AND USE THEREOF 1Globe Health Institute LLC (US) 2025-10-15 EP claimed
EP-4630010-A1 ASYMMETRIC SHORT DUPLEX RNA WITH INTERSPERSED DEOXYRIBONUCLEOTIDES AS A GENE SILENCING TECHNOLOGY AND USE THEREOF 1Globe Health Institute LLC (US) 2025-10-15 EP claimed
US-20020119570-A1 Targeted gene correction by single-stranded oligodeoxynucleotides THOMAS JEFFERSON UNIVERSITY 2002-08-29 US claimed
WO-2002026967-A2 TARGETED GENE CORRECTION BY SINGLE-STRANDED OLIGODEOXYNUCLEOTIDES THOMAS JEFFERSON UNIVERSITY (US) 2002-04-04 WO claimed
EP-0646648-B1 Method for producing polypeptide SUMITOMO CHEMICAL CO (JP) 2002-01-30 EP claimed
EP-0739898-B1 Phosphonomonoester nucleic acids, methods for their preparation and their use AVENTIS PHARMA GMBH (DE) 2001-09-26 EP claimed
US-5874553-A ANTIBODIES; INHIBITOR OF GENE EXPRESSION HOECHST AKTIENGESELLSCHAFT (DE) 1999-02-23 US claimed
US-5643744-A CONDENSATION OF AMINO ACID AND A NUCLEIC ACID ADAPTER IN PRESENCE OF RIBOSOMES AND AROMATIC TERTIARY AMINE BUT NO ENERGY SOURCE SUCH AS ATP OR GTP SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-01 US claimed
EP-0739898-A2 Phosphonomonoester nucleic acids, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1996-10-30 EP claimed
US-5434257-A Binding compentent oligomers containing unsaturated 3',5' and 2',5' linkages GILEAD SCIENCES, INC. (US) 1995-07-18 US claimed
WO-1995011911-A1 BINDING COMPETENT OLIGOMERS CONTAINING UNSATURATED 3',5' AND 2',5' LINKAGES GLAXO WELLCOME INC. (US) 1995-05-04 WO claimed
EP-0646648-A1 Method for producing polypeptide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-04-05 EP claimed