SCHEMBL26985708

SCHEMBL26985708

COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)C[C@@H]2O[Si](c2ccccc2)(c2ccccc2)C(C)(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TYMP P19971 6/20 0.48
ADORA1 P30542 2/20 0.47
POLB P06746 1/20 0.39
ENPP1 P22413 2/20 0.39
P2RY1 P47900 1/20 0.39
NT5E P21589 1/20 0.37
CHKA P35790 1/20 0.36
TRDMT1 O14717 1/20 0.36
CARM1 Q86X55 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24191239 0.92 ADORA1 (0.49) TYMPADORA1POLBENPP1P2RY1
SCHEMBL4820943 0.89 TYMP (0.50) TYMPADORA1POLBENPP1P2RY1
SCHEMBL29574745 0.86 TYMP (0.63) TYMPADORA1POLBENPP1P2RY1
SCHEMBL1774838 0.86 TYMP (0.63) TYMPADORA1POLBENPP1P2RY1
SCHEMBL1774839 0.86 TYMP (0.63) TYMPADORA1POLBENPP1P2RY1
SCHEMBL7871248 0.86 TYMP (0.63) TYMPADORA1POLBENPP1P2RY1
SCHEMBL29529385 0.86 TYMP (0.63) TYMPADORA1POLBENPP1P2RY1
SCHEMBL5224854 0.85 TYMP (0.47) TYMPADORA1POLBENPP1P2RY1
SCHEMBL7882460 0.84 TYMP (0.49) TYMPADORA1POLBENPP1P2RY1
SCHEMBL1332950 0.83 TYMP (0.49) TYMPADORA1POLBENPP1P2RY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4551580-A2 CRYSTALLINE MONOMERS FOR PREPARING ANTISENSE OLIGONUCLEOTIDES AND METHODS OF THEIR PREPARATION AND USE Eisai R&D Management Co., Ltd. (JP) 2025-05-14 EP disclosed
WO-2024010870-A2 CRYSTALLINE MONOMERS FOR PREPARING ANTISENSE OLIGONUCLEOTIDES AND METHODS OF THEIR PREPARATION AND USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-01-11 WO disclosed