Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 16/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26992429 | 1.00 | GRM2 (0.38) | GRM2KCNH2P2RX7HIF1APTGS1 | |
| SCHEMBL26989522 | 0.89 | GRM2 (0.47) | GRM2KCNH2HIF1A | |
| SCHEMBL26988136 | 0.89 | GRM2 (0.47) | GRM2KCNH2HIF1A | |
| SCHEMBL26987924 | 0.85 | GRM2 (0.39) | GRM2KCNH2 | |
| SCHEMBL26988260 | 0.85 | GRM2 (0.39) | GRM2KCNH2 | |
| SCHEMBL26988022 | 0.83 | GRM2 (0.37) | GRM2KCNH2 | |
| SCHEMBL26989451 | 0.83 | GRM2 (0.37) | GRM2KCNH2 | |
| SCHEMBL26988247 | 0.80 | GRM2 (0.37) | GRM2KCNH2HIF1APTGS1PTGS2 | |
| SCHEMBL26988379 | 0.80 | GRM2 (0.37) | GRM2KCNH2HIF1APTGS1PTGS2 | |
| SCHEMBL26992424 | 0.79 | GRM2 (0.58) | GRM2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008909-A1 | INHIBITORS OF CORONAVIRUS | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-11 | — | — | WO | disclosed |