Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30831657 | 1.00 | PDK2 (0.43) | PDK2KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30831453 | 0.95 | PDK2 (0.42) | PDK2KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL26995637 | 0.95 | PDK2 (0.42) | PDK2KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL26985807 | 0.89 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2GAAHTT | |
| SCHEMBL26985729 | 0.88 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL26985730 | 0.87 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2HTTEPHX2 | |
| SCHEMBL26985802 | 0.85 | PDK2 (0.40) | PDK2KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31506023 | 0.84 | BCHE (0.43) | PDK2KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31506013 | 0.84 | BCHE (0.43) | PDK2KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31755841 | 0.84 | BCHE (0.43) | PDK2KDM4EALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |