⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269984 | 0.73 | — | — | |
| SCHEMBL28309636 | 0.73 | — | — | |
| SCHEMBL1790592 | 0.73 | — | — | |
| SCHEMBL587593 | 0.73 | — | — | |
| SCHEMBL6084039 | 0.72 | — | — | |
| SCHEMBL343256 | 0.71 | — | — | |
| SCHEMBL107996 | 0.69 | TSHR (0.38) | — | |
| SCHEMBL107995 | 0.69 | TSHR (0.38) | — | |
| SCHEMBL231687 | 0.69 | — | — | |
| SCHEMBL12621827 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108371659-B | Limonin for treating autoimmune diseases | 澳门科技大学 | 2022-10-28 | — | — | CN | claimed |
| CN-105980387-B | Serine/threonine kinase inhibitor | 阵列生物制药公司 | 2019-04-19 | — | — | CN | claimed |
| US-9901566-B1 | Limonoids for treating autoimmune diseases | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (MO) | 2018-02-27 | — | — | US | claimed |
| EP-3089980-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2018-01-31 | — | — | EP | claimed |
| US-9670208-B2 | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2017-06-06 | — | — | US | claimed |
| EP-3089980-A1 | SERINE/THREONINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2016-11-09 | — | — | EP | claimed |
| US-20160304519-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2016-10-20 | — | — | US | claimed |
| CN-105980387-A | Serine/threonine kinase inhibitors | 阵列生物制药公司 | 2016-09-28 | — | — | CN | claimed |
| WO-2015103137-A1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2015-07-09 | — | — | WO | claimed |
| US-20110201642-A1 | Bioactive Compounds | BLUNT JOHN | 2011-08-18 | — | — | US | claimed |
| EP-2352746-A1 | BIOACTIVE COMPOUNDS | Universiti Teknologi Mara (MY) | 2011-08-10 | — | — | EP | claimed |
| WO-2010062159-A1 | BIOACTIVE COMPOUNDS | UNIVERSITI TEKNOLOGI MARA (MY) | 2010-06-03 | — | — | WO | claimed |
| EP-2129660-A2 | NICOTINAMIDE DERIVATIVES AS INHIBITORS OF H-PGDS AND THEIR USE FOR TREATING PROSTAGLANDIN D2 MEDIATED DISEASES | Pfizer Products Inc. (US) | 2009-12-09 | — | — | EP | claimed |
| WO-2008075172-A2 | NICOTINAMIDE DERIVATIVES AS INHIBITORS OF H-PGDS AND THEIR USE FOR TREATING PROSTAGLANDIN D2 MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2008-06-26 | — | — | WO | claimed |
| US-20080146569-A1 | Nicotinamide Derivatives | PFIZER INC. | 2008-06-19 | — | — | US | claimed |
| US-11904621-B2 | Thermal transfer recording sheet | CANON KABUSHIKI KAISHA (JP) | 2024-02-20 | — | — | US | disclosed |
| US-20230317700-A1 | CYTOTOXIC AND ANTI-MITOTIC COMPOUNDS, AND METHODS OF USING THE SAME | ZYMEWORKS BC INC. (CA) | 2023-10-05 | — | — | US | disclosed |
| CN-1193325-A | cell adhesion inhibitors | BIOGEN INC (US) | 1998-09-16 | — | — | CN | disclosed |
| EP-0490667-A2 | HIV protease inhibitors | JAPAN ENERGY CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |
| EP-0246749-A2 | Triazole herbicides | AgrEvo UK Limited (GB) | 1987-11-25 | — | — | EP | disclosed |