Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27004820 | 0.84 | LRRK2 (0.36) | FFAR1ADORA3LRRK2ADORA2AADORA1 | |
| SCHEMBL27006016 | 0.82 | FFAR1 (0.34) | FFAR1ADORA3LRRK2ADORA2AADORA1 | |
| SCHEMBL3590000 | 0.81 | HDAC8 (0.34) | HDAC8ALDH1A1ADORA3SMN1; SMN2ADORA2A | |
| SCHEMBL21584877 | 0.80 | HDAC8 (0.40) | HDAC8ALDH1A1SMN1; SMN2LRRK2PAK4 | |
| SCHEMBL31752587 | 0.77 | HDAC8 (0.41) | HDAC8SMN1; SMN2PAK4MET | |
| SCHEMBL3604719 | 0.77 | HDAC8 (0.44) | HDAC8ALDH1A1SMN1; SMN2PAK4MAPT | |
| SCHEMBL26983072 | 0.75 | HDAC8 (0.38) | HDAC8ALDH1A1FFAR1SMN1; SMN2 | |
| SCHEMBL27096718 | 0.73 | SMN1; SMN2 (0.41) | HDAC8ALDH1A1SMN1; SMN2LRRK2PAK4 | |
| SCHEMBL22001420 | 0.71 | PAK4 (0.46) | HDAC8ALDH1A1ADORA3SMN1; SMN2LRRK2 | |
| SCHEMBL27005996 | 0.70 | IRAK4 (0.39) | HDAC8ALDH1A1FFAR1SMN1; SMN2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |