SCHEMBL27007152

SCHEMBL27007152

CC=CC(=O)OCCCCC[SiH](C)OCC

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.44
ATM Q13315 1/20 0.43
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 2/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
APP P05067 4/20 0.35
PRKCA P17252 2/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28810780 0.94 ATM (0.46) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL22129657 0.86 HCAR2 (0.45) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL3738578 0.83 ATM (0.49) HCAR2ATMTSHRALDH1A1MAPT
SCHEMBL30767211 0.83 TSHR (0.59) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL28872434 0.80 ATM (0.58) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL20875241 0.80 ATM (0.58) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL25308300 0.80 HCAR2 (0.47) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL147607 0.80 ATM (0.47) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL7635714 0.80 ATM (0.47) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL5164063 0.80 ATM (0.47) HCAR2ATMTSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018358-A1 POLYSILOXANE-BASED RESIN AND UTILIZATION THEREOF KANEKA CORPORATION (JP) 2024-01-18 US disclosed