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SCHEMBL27009261

SCHEMBL27009261

CC(C)(C)OC(=O)N[C@@H]1CCCN(C(=O)c2cc(-c3ccc(C#N)c(F)c3)c(-c3cc4nnn(C(C)(C)CO)c4c(F)c3F)s2)C1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 19/20 0.45
▸ RET P07949 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27008229 0.89 KDM1A (0.57) KDM1A
SCHEMBL27015787 0.88 KDM1A (0.56) KDM1A
SCHEMBL27018802 0.88 KDM1A (0.56) KDM1A
SCHEMBL27008313 0.87 KDM1A (0.57) KDM1A
SCHEMBL27009343 0.86 KDM1A (0.43) KDM1A
SCHEMBL27006084 0.83 RET (0.43) KDM1ARET
SCHEMBL27006082 0.83 RET (0.43) KDM1ARET
SCHEMBL27015914 0.83 KDM1A (0.45) KDM1A
SCHEMBL27009363 0.82 KDM1A (0.44) KDM1ARET
SCHEMBL27005709 0.81 KDM4D (0.46) KDM1ARET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306520-A1 THIOPHENE COMPOUND AND APPLICATION THEREOF Medshine Discovery Inc. (CN) 2024-01-17 — — EP disclosed