Toluene

Toluene

SCHEMBL27009555

CC(=O)Nc1ncc(CN2CCC(C(N)=O)CC2)s1.Cc1ccccc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 18/20 0.72
▸ ACKR3 P25106 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27008584 0.84 OGA (1.00) OGA
SCHEMBL27008562 0.83 OGA (1.00) OGA
SCHEMBL16113559 0.82 OGA (0.80) OGAACKR3
SCHEMBL16112772 0.81 OGA (0.73) OGAACKR3
SCHEMBL27022520 0.81 OGA (1.00) OGA
SCHEMBL16112851 0.81 OGA (0.72) OGA
SCHEMBL16113632 0.80 OGA (0.64) OGAACKR3
SCHEMBL27022529 0.80 OGA (0.74) OGA
SCHEMBL17476241 0.80 OGA (0.66) OGA
SCHEMBL16112504 0.80 OGA (0.70) OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF MEDIFRON DBT INC. (KR) 2024-01-18 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018135-A1 COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF OGA, OGT, ENGASE OGA 1/4885ACKR3 4848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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