⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452325 | 0.78 | — | — | |
| SCHEMBL491152 | 0.75 | — | — | |
| SCHEMBL8011659 | 0.71 | — | — | |
| SCHEMBL4302760 | 0.71 | — | — | |
| SCHEMBL8018022 | 0.71 | — | — | |
| SCHEMBL4446100 | 0.71 | — | — | |
| SCHEMBL10670493 | 0.69 | — | — | |
| SCHEMBL7698042 | 0.69 | — | — | |
| SCHEMBL8441803 | 0.68 | TSHR (0.42) | — | |
| SCHEMBL8602004 | 0.68 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 475 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365524-A1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-16 | — | — | US | claimed |
| US-11713304-B2 | 2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2023-08-01 | — | — | US | claimed |
| EP-4183394-A1 | USE OF 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONE IN ANTIVIRAL | Academy of Military Medical Sciences (CN) | 2023-05-24 | — | — | EP | claimed |
| CN-115557907-A | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2023-01-03 | — | — | CN | claimed |
| CN-110023302-B | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2022-07-26 | — | — | CN | claimed |
| US-20220135536-A1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-05 | — | — | US | claimed |
| EP-3532468-B1 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AG (DE) | 2022-03-23 | — | — | EP | claimed |
| US-11130745-B2 | 2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH | BAYER AKTIENGELLSCHAFT (DE) | 2021-09-28 | — | — | US | claimed |
| US-11046658-B2 | Aminopyrazine derivatives as PI3K-γ inhibitors | INCYTE CORPORATION (US) | 2021-06-29 | — | — | US | claimed |
| US-20210188805-A9 | 2,4,5-TRISUBSTITUTED 1,2,4-TRIAZOLONES USEFUL AS INHIBITORS OF DHODH | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-24 | — | — | US | claimed |
| CN-1098908-C | Compound film with colour changing according to absorbed moisture quantity and making method thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 2003-01-15 | — | — | CN | claimed |
| CN-1374364-A | Prepn of curing allochroic film | GUANGZHOU INST OF CHEMISTRY (CN) | 2002-10-16 | — | — | CN | claimed |
| EP-0847383-B1 | MULTI-COMPONENT LIQUID AZODINITRILE MIXTURES | DU PONT (US) | 2001-11-07 | — | — | EP | claimed |
| CN-1060504-C | Solid composite colour film and manufacture thereof | GUANGZHOU CHEM INST (CN) | 2001-01-10 | — | — | CN | claimed |
| CN-1257905-A | Matrix structure controllable high polymer dispersed liquid crystal membrane and its preparing process | GUANGZHOU INST OF CHEMISTRY (CN) | 2000-06-28 | — | — | CN | claimed |
| CN-1223289-A | Compound film with colour changing according to absorbed moisture quantity and making method thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 1999-07-21 | — | — | CN | claimed |
| EP-0847383-A1 | MULTI-COMPONENT LIQUID AZODINITRILE MIXTURES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-17 | — | — | EP | claimed |
| US-5760192-A | FREE RADICAL, POLYMERIZATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-02 | — | — | US | claimed |
| CN-1178328-A | Solid composite colour film and manufacture thereof | GUANGZHOU CHEM INST (CN) | 1998-04-08 | — | — | CN | claimed |
| WO-1997008137-A1 | MULTI-COMPONENT LIQUID AZODINITRILE MIXTURES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-03-06 | — | — | WO | claimed |