Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349568 | 1.00 | CYP19A1 (0.46) | CYP19A1TSHRMAOBARHSD17B10 | |
| SCHEMBL27018775 | 1.00 | CYP19A1 (0.46) | CYP19A1TSHRMAOBARHSD17B10 | |
| SCHEMBL27779717 | 1.00 | CYP19A1 (0.46) | CYP19A1TSHRMAOBARHSD17B10 | |
| SCHEMBL11395645 | 0.90 | KDM1A (0.41) | CYP19A1MAOBARHSD17B10ADORA3 | |
| SCHEMBL11386397 | 0.90 | KDM1A (0.41) | CYP19A1MAOBARHSD17B10ADORA3 | |
| SCHEMBL11386400 | 0.90 | KDM1A (0.41) | CYP19A1MAOBARHSD17B10ADORA3 | |
| SCHEMBL11386399 | 0.90 | KDM1A (0.41) | CYP19A1MAOBARHSD17B10ADORA3 | |
| SCHEMBL11394360 | 0.90 | KDM1A (0.41) | CYP19A1MAOBARHSD17B10ADORA3 | |
| SCHEMBL26328190 | 0.81 | MAOB (0.43) | CYP19A1MAOBCYP3A4MAPTCYP1A2 | |
| SCHEMBL27006295 | 0.81 | RET (0.40) | MAOBHSD17B10KDM4ELDHAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101701227-A | Method for preparing optically pure 2-hydroxy-4-phenyl butyric acid with lactonase | UNIV EAST CHINA SCIENCE & TECH | 2010-05-05 | — | — | CN | claimed |
| US-20240018076-A1 | PROCESS FOR THE PREPARATION OF A CHIRAL TRIOL | HOFFMANN-LA ROCHE INC. (US) | 2024-01-18 | — | — | US | disclosed |
| US-20240018076-A1 | PROCESS FOR THE PREPARATION OF A CHIRAL TRIOL | HOFFMANN-LA ROCHE INC. (US) | 2024-01-18 | — | — | US | disclosed |
| CN-101701227-A | Method for preparing optically pure 2-hydroxy-4-phenyl butyric acid with lactonase | UNIV EAST CHINA SCIENCE & TECH | 2010-05-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018076-A1 | PROCESS FOR THE PREPARATION OF A CHIRAL TRIOL | HMGCR, CETP, MTTP | CYP19A1 313/4885TSHR 422/4885MAOB 2879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.